A4IQK7

PR
Gene name
namA
Protein name
NADPH dehydrogenase
Names
Species
Geobacillus thermodenitrificans (strain NG80-2)
KEGG Pathway
gtn:GTNG_2262
EC number
1.6.99.1: With other acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

90-168 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4IQK7

Entry ID Method Resolution Chain Position Source
AF-A4IQK7-F1 Predicted AlphaFoldDB

No variants for A4IQK7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4IQK7

No associated diseases with A4IQK7

1 regional properties for A4IQK7

Type Name Position InterPro Accession
domain NADH:flavin oxidoreductase/NADH oxidase, N-terminal 5 - 324 IPR001155

Functions

Description
EC Number 1.6.99.1 With other acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
NADPH dehydrogenase activity Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
pentaerythritol trinitrate reductase activity Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.

1 GO annotations of biological process

Name Definition
response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNTVLFSPYT TRGLTLKNRI VMSPMCMYSC DTKDGTVRTW HKIHYPARAI GQVGLIIVEA
70 80 90 100 110 120
TGVTPQGRIS EHDLGIWDDD HIHGLHELVG LVKEHGAAIG IQLAHAGRKS EVPGEIIAPS
130 140 150 160 170 180
AIPFNESSPT PKEMTKADIE KTVQAFQDGA RRAKKAGFDV IEIHAAHGYL INEFLSPLSN
190 200 210 220 230 240
RRQDEYGGSP ENRYHFLGEV IDAVREVWDG PLFVRISASD YHPDGLTVKD YVPYVKRMKE
250 260 270 280 290 300
QGVDLVDVSS GAVVPARIDV YPGYQVPFAE FIRREAGIPT GAVGLITSGW QAEEVLHNGR
310 320 330
ADLVFLGREL LRNPYWPYAA AKELGVKIEA PVQYERGWRF