A4FWM4
Gene name |
purO |
Protein name |
IMP cyclohydrolase |
Names |
IMP synthase, Inosinicase |
Species |
Methanococcus maripaludis (strain C5 / ATCC BAA-1333) |
KEGG Pathway |
mmq:MmarC5_0283 |
EC number |
3.5.4.10: In cyclic amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4FWM4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4FWM4-F1 | Predicted | AlphaFoldDB |
No variants for A4FWM4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4FWM4 | |||||
No associated diseases with A4FWM4
1 regional properties for A4FWM4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Inosine monophosphate cyclohydrolase-like | 2 - 194 | IPR020600 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.4.10 | In cyclic amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| IMP cyclohydrolase activity | Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 'de novo' IMP biosynthetic process | The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYIGRFLVFG | KTEEGYPFVT | YRVSSRSFPN | RLAKVMDDDT | VSILPKELEE | MFKNPYITYN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CVKLVGDVAV | ATNGSHTDII | ADKIKLGLPI | RDALSYSLLT | MDYEKDDYNT | PRIAVVITKD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EAYMGYVTDS | DVRIKKVELE | AGKAYYLGVY | DACKITEHQV | ISVTGKTAED | LTKFVMDYEE |
| 190 | 200 | ||||
| FEKPVTAATV | LVKDGFKLAT | L |