A4FWE6
Gene name |
purP |
Protein name |
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase |
Names |
5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase |
Species |
Methanococcus maripaludis (strain C5 / ATCC BAA-1333) |
KEGG Pathway |
mmq:MmarC5_0205 |
EC number |
6.3.4.23: Other carbon--nitrogen ligases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A4FWE6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A4FWE6-F1 | Predicted | AlphaFoldDB |
No variants for A4FWE6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A4FWE6 | |||||
No associated diseases with A4FWE6
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.4.23 | Other carbon--nitrogen ligases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ligase activity, forming carbon-nitrogen bonds | Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 'de novo' IMP biosynthetic process | The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIPKEEIMGI | FEKYNKDEVT | IVTVGSHTSL | HILKGAKLEG | FSTAVITTKD | RAIPYKRFGV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ADKFIYVDQF | SDISKEEIQQ | QLRDMNAIIV | PHGSFIAYCG | LDNVEDSFKV | PMFGNRAILR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WEAERDLEGQ | LLGESGLRIP | KKYGGPDDID | GPVMVKFPGA | RGGRGYFPCS | TVEEFWRKIA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EFKAKGILTE | DDVKKAHIEE | YVVGANYCIH | YFYSPLKDQV | ELMGIDRRYE | SSIDGLVRVP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKDQLELNVD | PSYVITGNFP | VVIRESLLPQ | VFDIGDKLSA | KSKELVKPGM | LGPFCLQSLC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NDNLELVVFE | MSARVDGGTN | TFMNGSPYSC | LYTGEPLSMG | QRIAKEIKLA | LELGMIDKVL |
| S |