A4FPT4

PR
Gene name
nuoH
Protein name
NADH-quinone oxidoreductase subunit H
Names
NADH dehydrogenase I subunit H, NDH-1 subunit H
Species
Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
KEGG Pathway
sen:SACE_6895
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

351-441 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4FPT4

Entry ID Method Resolution Chain Position Source
AF-A4FPT4-F1 Predicted AlphaFoldDB

No variants for A4FPT4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4FPT4

No associated diseases with A4FPT4

2 regional properties for A4FPT4

Type Name Position InterPro Accession
domain NADH-quinone oxidoreductase, subunit D 170 - 440 IPR001135
conserved_site NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site 93 - 104 IPR014029

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
quinone binding Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNTAELLAD DPIWLVLIKV VAIFAFLVVM TLFSIWAERR VIGRMQHRPG PNRAGPFGLL
70 80 90 100 110 120
QSLADGLKLA FKEDIRPVLA DKWVYFLAPV ISATPALVAF SVIPIGGEVS VFGQQTALQL
130 140 150 160 170 180
VELPVGLLVV LACASIGVYG IVLAGWSSGS PYPLLGSLRS AAQVISYEIA MGLSFVAVIM
190 200 210 220 230 240
YAGTLSTSGI VEAQKDGWFA LLLPFSFLVY VVSMVGETNR APFDLPEAES ELVGGFHTEY
250 260 270 280 290 300
SSLKFALFFL AEYINMVTVS ALATTLFLGG WHAPWPLSAI GGGVLNTGWW PVLWFLGKTL
310 320 330 340 350 360
AFLFVFVWLR GTLPRLRYDQ FMNLGWKFLV PLSLLWIIAV TVIRALRNND AVTSQQFLIA
370 380 390 400 410 420
GGVVIAVLLV ATFLIPDRKV PESDGEVPLA GSGYPIPPLD LEVPKAPPRR SAVHAGAQAA
430 440
PAGQLPGEGA GSTKEEPNGS V