A3QBN1

PR
Gene name
cca
Protein name
Multifunctional CCA protein
Names
Species
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
KEGG Pathway
slo:Shew_1008
EC number
2.7.7.72: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

231-305 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3QBN1

Entry ID Method Resolution Chain Position Source
AF-A3QBN1-F1 Predicted AlphaFoldDB

No variants for A3QBN1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3QBN1

No associated diseases with A3QBN1

3 regional properties for A3QBN1

Type Name Position InterPro Accession
domain Polymerase, nucleotidyl transferase domain 34 - 141 IPR002934
domain 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain 44 - 149 IPR006116
domain tRNA nucleotidyltransferase, substrate binding 155 - 278 IPR015329

Functions

Description
EC Number 2.7.7.72 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

9 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.
CTP:3'-cytidine-tRNA cytidylyltransferase activity Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate.
CTP:tRNA cytidylyltransferase activity Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate.
cyclic-nucleotide phosphodiesterase activity Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
tRNA binding Binding to a transfer RNA.
tRNA cytidylyltransferase activity Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1).

2 GO annotations of biological process

Name Definition
RNA repair Any process that results in the repair of damaged RNA.
tRNA 3'-terminal CCA addition Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKIYLVGGAV RDQLLNIPIK DRDYMVVGAT VQEMLDKGYR QVGKDFPVFL HPKTQQEYAL
70 80 90 100 110 120
ARTERKTGVG YGGFSVYAAP DVTLEEDLLR RDLTINAIAQ DETGRVFDPY GGQADIEQRL
130 140 150 160 170 180
LRHVSDAFVE DPLRVLRVAR FAARFQPLGF KVAPETMALM QRIAASGELE ALTPERVFQE
190 200 210 220 230 240
LDKALSTEAP QVFFEVLREA GGLAILFPEI EALFGIPQPE QWHPEIDTGI HTLMVLEQAA
250 260 270 280 290 300
RLSQDKQVRF AALVHDLGKA LSPKEHLPKH HGHGQKGLPL IRALCERFRV PNDYRDLALL
310 320 330 340 350 360
VSDQHQNIHN AFELRAETMV KLFDKADLWR KPERLPQLLL ACEADCKGRT GLKERPYPQG
370 380 390 400 410
AYVQHCFELA RNVAIKPIIE AGFKGAEIKA QLHKQRVEVI DQYKRKTAVN AKP