A3PMI4
Gene name |
pqqC |
Protein name |
Pyrroloquinoline-quinone synthase |
Names |
Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C |
Species |
Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) (Rhodobacter sphaeroides) |
KEGG Pathway |
rsh:Rsph17029_2448 |
EC number |
1.3.3.11: With oxygen as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A3PMI4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A3PMI4-F1 | Predicted | AlphaFoldDB |
No variants for A3PMI4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A3PMI4 | |||||
No associated diseases with A3PMI4
1 regional properties for A3PMI4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Thiaminase-2/PQQC | 23 - 233 | IPR004305 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.3.3.11 | With oxygen as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| pyrroloquinoline-quinone synthase activity | Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular aromatic compound metabolic process | The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. |
| pyrroloquinoline quinone biosynthetic process | The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLDLSTSLS | PARPLESADA | MEERLREIGA | ARYHDRHPFH | HMLHGGELTK | GQVQAWALNR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YYYQCTIPVK | DAVVISRFRD | RATRIEWRHR | LEDHDGAEGA | EGGIDRWLIL | TDGLGLDRAY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VESTDGILPA | TRFAVEAYVH | FVRDRSPLEA | IASCLTELFA | PNIHATRISG | MLSHYDFINP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TVMAYFQRRL | TQAPRDADYA | LRYVRDHART | PEERAAVCNA | LIFKTQVLWT | QLDALHHAYV |
| 250 | |||||
| LGHVPPGAFV | PEEMR |