Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A3N211

Entry ID Method Resolution Chain Position Source
AF-A3N211-F1 Predicted AlphaFoldDB

No variants for A3N211

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3N211

1 associated diseases with A3N211

[MIM: 605389]: Hypotrichosis 1 (HYPT1)

A rare form of non-syndromic hereditary hypotrichosis without characteristic hair shaft anomalies. Affected individuals typically show normal hair at birth, but hair loss and thinning of the hair shaft start during early childhood and progress with age. HYPT1 inheritance is autosomal dominant. {ECO:0000269|PubMed:20393562}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID
  • A rare form of non-syndromic hereditary hypotrichosis without characteristic hair shaft anomalies. Affected individuals typically show normal hair at birth, but hair loss and thinning of the hair shaft start during early childhood and progress with age. HYPT1 inheritance is autosomal dominant. {ECO:0000269|PubMed:20393562}. Note=The disease is caused by variants affecting the gene represented in this entry.

1 regional properties for A3N211

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 71 - 364 IPR017452

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
nucleic acid binding Binding to a nucleic acid.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVQWKTLTKR SQGANFEQKA REFLERNGLK FIAANQQFKC GELDLIMRQG DTFVFVEVRQ
70 80 90 100 110 120
RKSNRFGSAV ESIDYRKQQK WLDAANMWLF TRHKQSLDTA NCRFDVVAFE GNDPPLWIPN
FLG