Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A3MRW0

Entry ID Method Resolution Chain Position Source
AF-A3MRW0-F1 Predicted AlphaFoldDB

No variants for A3MRW0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3MRW0

No associated diseases with A3MRW0

4 regional properties for A3MRW0

Type Name Position InterPro Accession
domain Ribosomal protein S3, C-terminal 120 - 202 IPR001351
domain K Homology domain, type 2 39 - 110 IPR004044
domain K Homology domain 60 - 125 IPR004087
conserved_site Ribosomal protein S3, conserved site 163 - 197 IPR018280

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGQKIHPTGF RLAVSRNWAS RWYANNNNFA AMLQEDIGVR EYLKKKLKNA SVGRVVIERP
70 80 90 100 110 120
AKNARITIFS SRPGVVIGKK GEDIELLKTE LQRRMGVPVH VNIEEIRKPE TDAQLIADSI
130 140 150 160 170 180
TQQLERRIMF RRAMKRAMQN AMRLGAQGIK IMSAGRLNGI EIARTEWYRE GRVPLHTLRA
190 200 210 220 230 240
DIDYATSEAK TTYGIIGVKV WVYKGDTLGR NDAPVVEEVT EDKRPRRNAR PGDRRPRRDG
250 260
EGGAPGARRG GPRRGAGKPE DGKTGE