A3M3C8

PR
Gene name
ppk
Protein name
Polyphosphate kinase
Names
ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase
Species
Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
KEGG Pathway
acb:A1S_0990
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

643-693 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3M3C8

Entry ID Method Resolution Chain Position Source
AF-A3M3C8-F1 Predicted AlphaFoldDB

No variants for A3M3C8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3M3C8

No associated diseases with A3M3C8

4 regional properties for A3M3C8

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 134 - 331 IPR024953
domain Polyphosphate kinase N-terminal domain 19 - 124 IPR025198
domain Polyphosphate kinase C-terminal domain 2 511 - 685 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 339 - 503 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNTAITATTP TEYSYNDRYI NRELSILDFH LRVLEQAVDP LHPLLERMNF LLIFSRNLDE
70 80 90 100 110 120
FFEIRVAGVM EQFALGNESR SPDGLTPRQV LQKISETAHA AIERQYRILN EEILPKLREE
130 140 150 160 170 180
DICFLRRGEL TPAQSAWVKK YFQEQVAPVL TPISLDPAHP FPRLVNKSLN FIVTLEGKDA
190 200 210 220 230 240
FGRQIDLAVV PAPRSLPRVV RLPDELTGGK EHHVMLSAII HEHVSDLFPG MTATGCYQFR
250 260 270 280 290 300
VTRNADLALN EDVEDLAKAL KGELSSRRFG RAVRLEVTQN CPQHIYEYLL EEFDLNEEQL
310 320 330 340 350 360
YKVDGPVNLA RLVSNFKRPH LRYDSHTPVV PKVFKKTESI FSAMQKQDIL LHHPFESFAP
370 380 390 400 410 420
VIQLLREAAR DPQVLAIKQT LYRSGADSEI VQVLAEAARN GKEVTAVIEL RARFDEESNI
430 440 450 460 470 480
EVANVLQEAG AVVVYGIVGY KTHAKMIMVV RRENNKLVRY VHLGTGNYHA MNARIYTDYG
490 500 510 520 530 540
LMTTDKDLCE DVHRIFQELT GMGKMAKLKK LLHAPFTLHA QLINFIDEEI ANAKAGRKAQ
550 560 570 580 590 600
IIVKVNALTE VQLINKLYEA SQAGVQVDLI IRYDLLFTSG ITKFIGKHSG TFNCRTVSFE
610 620 630 640 650 660
HTRVYYFSNN GDARIYCSSA DWMDRNLFNR VEACFPIEDP ALKKRIYQQG LLNYLQDNQQ
670 680 690
AWLLQGDGTW VRAQPAAGEK LHNAQRELLE TFK