A3LY92

PR
Gene name
HSM3 (PICST_62139)
Protein name
DNA mismatch repair protein HSM3
Names
Species
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
KEGG Pathway
pic:PICST_62139
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3LY92

Entry ID Method Resolution Chain Position Source
AF-A3LY92-F1 Predicted AlphaFoldDB

No variants for A3LY92

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3LY92

No associated diseases with A3LY92

2 regional properties for A3LY92

Type Name Position InterPro Accession
domain DNA mismatch repair protein HSM3, C-terminal domain 319 - 484 IPR040752
domain DNA mismatch repair protein HSM3, N-terminal domain 17 - 255 IPR041335

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPAPATTTSV DEQTLSVIDH LTKSYDNKSE IDSTLIDDYI TVLGSIDLLG AIADFIPIIN
70 80 90 100 110 120
HILTDNLYHQ IDPNRLLIEL LQKIVSRLSF GQIVSVYSPE FIVSSLASSD NVPITKLCLS
130 140 150 160 170 180
IIIQKLHEPE TVSFIAENCI SFILLKNYLS DAKLDLGIVN QIELYVNSLI LNDVTNLLEE
190 200 210 220 230 240
ILTDTKFVIL YNSIRNSENT ILLARLLDFI LILLTYKVDL PLDPRLYTFS NVEIVTFKDD
250 260 270 280 290 300
PLFLILLVQF YVKLVQFSVL EEVSPVIGNF VNLYKDPTTD DFVKVEVIDI LVKLSYATNS
310 320 330 340 350 360
LLIEYGLELA LNSELFKSHN LIKVYEYNEP DIKLLSNVNP DLIVHSSNVI YEDVLSNLSL
370 380 390 400 410 420
LNNKQYFPIL LNFIGSTDVF PRLEQDYFTT KLKHLPADKL YVILLEFSKF SHSRKFLLSN
430 440 450 460 470 480
ATLTNDYLLD NDNLTFVNNE LWHTKLQVLE NLVNATDSDS PELAHWKPYL QDSFNLMRHG
490
KKIRDVVPQV SILDETL