Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A3LRH4

Entry ID Method Resolution Chain Position Source
AF-A3LRH4-F1 Predicted AlphaFoldDB

No variants for A3LRH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3LRH4

No associated diseases with A3LRH4

8 regional properties for A3LRH4

Type Name Position InterPro Accession
domain DNA topoisomerase, type IIA, domain A 693 - 1174 IPR002205
domain Histidine kinase/HSP90-like ATPase 79 - 224 IPR003594
domain TOPRIM domain 455 - 572 IPR006171
domain DTHCT 1435 - 1522 IPR012542
domain DNA topoisomerase, type IIA, subunit B, domain 2 266 - 426 IPR013506
conserved_site DNA topoisomerase, type IIA, conserved site 459 - 467 IPR018522
domain C-terminal associated domain of TOPRIM 573 - 711 IPR031660
domain DNA topoisomerase 2, TOPRIM domain 455 - 575 IPR034157

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRYARTVRF SQVGNSVRTS SGSFGPIRTI FISSHDRKSP SHSLSPISNL PNHNDSSTER
70 80 90 100 110 120
ARKTLDDDFQ RKIKYDELKT RKRIEDLRAL TKKVSQLVKQ KQELSKIAKI PVPSDEIKKL
130 140 150 160 170 180
KSVEDVVKVT KSQHVATVRT NIPEPETVTT HIEKEESEFV MEQNAFIVPA TPIPEEIAKR
190 200 210 220 230 240
LGLALRYLVS ETNQNWTLVL DQLKADRGFK DLPYTTVVDF LTKIPASELQ KVIPKVDQLL
250 260 270 280 290 300
KEAKIPKTAK ILNLYIASLA SGSAVPNQVI QILENYCKRI RKLKKGKLPK RTCEVMVQAY
310 320 330 340 350 360
GKNGNINRIQ DLLSEMKLHK IEISGMALTN ILATCVYKAR DHKQAVEIFD TMRFQKEVYK
370 380 390 400 410 420
PGTRAYQDII VSYVNNDDIE KAIDIYREMI TEKIEPNQQI MVALARGCAS REAFKFKSWD
430 440 450 460 470 480
FIFEINRNNW TPTLPTYEYM LYLSSRDGDL ALTRALYSRL LKDNTVSLRS FNFLLLAYSK
490 500 510 520 530 540
ARLSDDLGEP FLINADEKGR KFRFNVIDRS GISDPTNQFP FLPFNELTTK EQIMAESSAI
550 560 570 580 590 600
WAHACLNNSE LINSESTTSY LNIASERGTL SDFIDRMEGS TFLDEKINNV LSGVVIEEPD
610 620 630 640 650 660
VVVETTDFLT QKSSAHEKYD ETSIVKSPIL KSIQSKRTPR VSLTYVVALK AAGKFNNYNF
670 680 690 700 710 720
ANRIWQERGK FRKTETFKKL PRTEKDKLDF QFATQMVRTL TELNLLEDAL AVLKSTEYQF
730 740 750 760 770
RWTWKELDVL KSAAIRQGNT NVAQTVRSIA RRAQLTYEGK IRRKDYKRYV MQRGY