A3LQL9

PR
Gene name
PAN3
Protein name
PAN2-PAN3 deadenylation complex subunit PAN3
Names
PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3
Species
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
KEGG Pathway
pic:PICST_76360
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-142 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3LQL9

Entry ID Method Resolution Chain Position Source
AF-A3LQL9-F1 Predicted AlphaFoldDB

No variants for A3LQL9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3LQL9

No associated diseases with A3LQL9

2 regional properties for A3LQL9

Type Name Position InterPro Accession
domain Zinc finger, CCCH-type 7 - 36 IPR000571
domain Pan3 pseudokinase domain 499 - 627 IPR041332

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
PAN complex A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
nuclear-transcribed mRNA poly(A) tail shortening Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNLNLDSAKD TLCKNILIYG YCKFENKGCA FSHHKPNVGQ PPVSASSSSG YSGNSSPAEA
70 80 90 100 110 120
KRKFNLNTPS FQPSNVQNIT SKFAALSPKV KEIPVFVPSG GSGGAANTPN NGADANELLS
130 140 150 160 170 180
QKKFNASTPS FMPAGFGSEY PSSPNTSGAG QPPNPYLTGN GHPASMAQSS GADVYYQQQA
190 200 210 220 230 240
ASYPLQYHLY APAPPPRLTI PLPPHETNAN SMFIPNDLRE TLQKKNEATL QTLPRSNLPE
250 260 270 280 290 300
HINIYHSLVP IDKSYDPKSK VWDVPSSLYK VFSSVDGNPY ALRKIELNFP IINEAPFKTI
310 320 330 340 350 360
KKWRSVKNAN VTQLQEAFTS MAFGKSCLVV VYDYFPNSST LIDHHKRIGT RTEPITEDLL
370 380 390 400 410 420
WNYLVQLVNA LMAIHAKGLA ARSALDLTKI IVTNKNRIRL SNLAISDILN FEKDEEEISK
430 440 450 460 470 480
SNRYFQGLQR EDIKKLGRIL LSLSTLTIPN TLRNNDTGEL LRHLKTSSTI SFSDEFIQVL
490 500 510 520 530 540
TVLNEDTVEF DLDRFSQRYL TTRLFSTINN LEDSTDFMES QITTELENAR LFRLLTKLNF
550 560 570 580 590 600
IIDRPEAKDW TENSNKYIIK LFRDYIFFQH DEYGKPVVDL SRVLTNLNKL DAGIDEKFLL
610 620
VSRDEKNCII VSYKEIRDTI DSVFRNLTRD