A3DHP2

PR
Gene name
atpD
Protein name
V-type ATP synthase subunit D
Names
V-ATPase subunit D
Species
Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum)
KEGG Pathway
cth:Cthe_2269
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

77-149 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3DHP2

Entry ID Method Resolution Chain Position Source
AF-A3DHP2-F1 Predicted AlphaFoldDB

No variants for A3DHP2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3DHP2

No associated diseases with A3DHP2

4 regional properties for A3DHP2

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 133 - 346 IPR000194
domain AAA+ ATPase domain 145 - 330 IPR003593
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 6 - 75 IPR004100
active_site ATPase, alpha/beta subunit, nucleotide-binding domain, active site 337 - 346 IPR020003

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
proton-transporting ATPase activity, rotational mechanism Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.

1 GO annotations of biological process

Name Definition
proton motive force-driven plasma membrane ATP synthesis The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAIMRVNPTR MELTRLKKRL QVARRGHKLL KDKLDELMKQ FLDLVRKNKE LREKVEEMLM
70 80 90 100 110 120
KAHQDFLIAR AVMSSEGLEA ALMLPKQSIS LDVSTQNIMS VEVPVLKFTT SSSDESDIYP
130 140 150 160 170 180
YGFASTSGEL DGAILTLSKV LPYMLELAQM EKSSQLLAQE IEKTRRRVNA LEYVMIPQLT
190 200 210 220
ETIKYISMKL DENERGNITR LMKVKDMMLE QAHNFKEKLN EA