A3CXJ6
Gene name |
mptA |
Protein name |
GTP cyclohydrolase MptA |
Names |
GTP cyclohydrolase IV |
Species |
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) |
KEGG Pathway |
mem:Memar_2173 |
EC number |
3.5.4.39: In cyclic amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A3CXJ6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A3CXJ6-F1 | Predicted | AlphaFoldDB |
No variants for A3CXJ6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A3CXJ6 | |||||
No associated diseases with A3CXJ6
No regional properties for A3CXJ6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A3CXJ6 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.4.39 | In cyclic amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP cyclohydrolase activity | Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. |
| iron ion binding | Binding to an iron (Fe) ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELPDVQSSL | PEVRINLTRV | GVKNVQKLVE | VARPGKRPVI | FISNFDVFVD | LPGSLKGANL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SRNFEVIDDV | LQQAIDGDVN | EIEELCSAVA | RKLLDRHEYA | ERTEVRMRSK | FMVRRETPVS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ETSCHEVVNV | HAKAIAQRNE | GDPIIRKSIG | AEVTGMTACP | CAQNIMKDHA | LHVLENLGVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EDKIEAFFNE | VPMATHNQRG | RGFLCIEIDD | DQHISLEKII | KILKDSMSAR | IYELLKRGDE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SYVVMEAHKN | PRFVEDCVRE | MARKVIAQFH | DLPGDSVVTI | KQTNEESIHQ | HNAYAERKAT |
| 310 | |||||
| IAELVSEMDK | GTL |