A2ZAB5

PR
Gene name
SAPK3 (REK)
Protein name
Serine/threonine-protein kinase SAPK3
Names
Osmotic stress/abscisic acid-activated protein kinase 3, Protein kinase REK
Species
Oryza sativa subsp indica (Rice)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

247-334 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

143-165 (Activation loop from InterPro)

Target domain

5-261 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for A2ZAB5

Entry ID Method Resolution Chain Position Source
AF-A2ZAB5-F1 Predicted AlphaFoldDB

No variants for A2ZAB5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2ZAB5

No associated diseases with A2ZAB5

3 regional properties for A2ZAB5

Type Name Position InterPro Accession
domain Protein kinase domain 5 - 261 IPR000719
active_site Serine/threonine-protein kinase, active site 120 - 132 IPR008271
binding_site Protein kinase, ATP binding site 11 - 34 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
abscisic acid-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEERYEALKE LGAGNFGVAR LVRDKRSKEL VAVKYIERGK KIDENVQREI INHRSLRHPN
70 80 90 100 110 120
IIRFKEVCLT PTHLAIVMEY AAGGELFEQI CTAGRFSEDE ARYFFQQLIS GVSYCHSLEI
130 140 150 160 170 180
CHRDLKLENT LLDGSPTPRV KICDFGYSKS ALLHSKPKST VGTPAYIAPE VLSRKEYDGK
190 200 210 220 230 240
VADVWSCGVT LYVMLVGSYP FEDPGDPRNF RKTISRILGV QYSIPDYVRV SSDCRRLLSQ
250 260 270 280 290 300
IFVADPSKRI TIPEIKKHTW FLKNLPKEIS EREKADYKDT DAAPPTQAVE EIMRIIQEAK
310 320 330
VPGDMAAADP ALLAELAELK SDDEEEAADE YDTY