A2YNT8

PR
Gene name
SAPK2 (OsI_26911)
Protein name
Serine/threonine-protein kinase SAPK2
Names
Osmotic stress/abscisic acid-activated protein kinase 2
Species
Oryza sativa subsp indica (Rice)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

123-192 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

142-164 (Activation loop from InterPro)

Target domain

4-260 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for A2YNT8

Entry ID Method Resolution Chain Position Source
AF-A2YNT8-F1 Predicted AlphaFoldDB

No variants for A2YNT8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2YNT8

No associated diseases with A2YNT8

3 regional properties for A2YNT8

Type Name Position InterPro Accession
domain Protein kinase domain 4 - 260 IPR000719
active_site Serine/threonine-protein kinase, active site 119 - 131 IPR008271
binding_site Protein kinase, ATP binding site 10 - 33 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

3 GO annotations of biological process

Name Definition
abscisic acid-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
protein phosphorylation The process of introducing a phosphate group on to a protein.
seed germination The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MERYEVIKDI GSGNFGVAKL VRDVRTKELF AVKFIERGQK IDENVQREIM NHRSLRHPNI
70 80 90 100 110 120
VRFKEVVLTP THLAIVMEYA AGGELFERIC SAGRFSEDEA RFFFQQLISG VSYCHSMQIC
130 140 150 160 170 180
HRDLKLENTL LDGSIAPRLK ICDFGYSKSS VLHSQPKSTV GTPAYIAPEV LARKEYDGKV
190 200 210 220 230 240
ADVWSCGVTL YVMLVGAYPF EDPDEPRNFR KTITRILSVQ YMVPDYVRVS MECRHLLSRI
250 260 270 280 290 300
FVANPEQRIT IPEIKNHPWF LKNLPIEMTD EYQMSVQMND INTPSQGLEE IMAIIQEARK
310 320 330
PGDGSKFSGQ IPGLGSMELD DIDTDDIDVE DSGDFVCAL