Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A2YCH5

Entry ID Method Resolution Chain Position Source
AF-A2YCH5-F1 Predicted AlphaFoldDB

No variants for A2YCH5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2YCH5

No associated diseases with A2YCH5

2 regional properties for A2YCH5

Type Name Position InterPro Accession
domain Protein kinase domain 24 - 419 IPR000719
active_site Serine/threonine-protein kinase, active site 142 - 154 IPR008271

Functions

Description
EC Number 2.7.11.22 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
cyclin-dependent protein serine/threonine kinase activity Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
RNA polymerase II CTD heptapeptide repeat kinase activity Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = ADP + H+ + phosphorylated RNA polymerase II.

2 GO annotations of biological process

Name Definition
maintenance of root meristem identity The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAIGGGGGGG SWSIHGRPDV TSRYEVLGRA GSGAYADVYR GRRRSDGAPV ALKEVHDAVS
70 80 90 100 110 120
ARREADALLA AAPSRHVVAL LDHFPGGDHD DDVLVLEWLP LDLSAVVRAA AAARPSAPPA
130 140 150 160 170 180
AQRKRWMLQV LEGVAACHSA GVVHRDLKPA NLLISEDGVL KVADLGQARI LQETGTYQGM
190 200 210 220 230 240
HPYEQSSGVE PWVSQQRAVL HGVKENHPSH DSETQTGQEP ERLTAADYLH EMDQLRAKST
250 260 270 280 290 300
HGDVDKMSLQ DGNASCLATC STADIDDDPF RASYSYDAEE GMLEEESGAF TSCVGTRWFR
310 320 330 340 350 360
APELLYGSTN YGQEVDLWSL GCILAELFNL EPIFPGTSDI DQIGRIISVL GNITEETFPG
370 380 390 400 410 420
CSNLPDYNKI FFNKVEKPIG LEACLPDRSA SEVSIIKRLL CYDPTKRASA ADLLNDPYFA
430 440 450 460 470
EEPLPVPIEG LQVPESKDED DDSTEEWANF RGGDSDSDFD EFGSMDVTKT DKGFSIRFS