A2XL32

PR
Gene name
ERS1 (OSERS)
Protein name
Probable ethylene response sensor 1
Names
Species
Oryza sativa subsp indica (Rice)
KEGG Pathway
EC number
2.7.13.3: Protein-histidine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

89-171 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2XL32

Entry ID Method Resolution Chain Position Source
AF-A2XL32-F1 Predicted AlphaFoldDB

No variants for A2XL32

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2XL32

No associated diseases with A2XL32

13 regional properties for A2XL32

Type Name Position InterPro Accession
domain Protein kinase domain 613 - 875 IPR000719
domain Ephrin receptor ligand binding domain 28 - 206 IPR001090
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 614 - 871 IPR001245
conserved_site Tyrosine-protein kinase, receptor class V, conserved site 182 - 202 IPR001426-1
conserved_site Tyrosine-protein kinase, receptor class V, conserved site 247 - 267 IPR001426-2
domain Sterile alpha motif domain 901 - 968 IPR001660
domain Fibronectin type III 328 - 432 IPR003961-1
domain Fibronectin type III 436 - 529 IPR003961-2
active_site Tyrosine-protein kinase, active site 735 - 747 IPR008266
binding_site Protein kinase, ATP binding site 619 - 646 IPR017441
domain Tyrosine-protein kinase, catalytic domain 613 - 871 IPR020635
domain Ephrin receptor, transmembrane domain 538 - 610 IPR027936
domain Ephrin type-A receptor 2, ligand binding domain 28 - 201 IPR034263

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

1 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDGCDCIEPL WPTDELLIKY QYISDFFIAL AYFSIPLELI YFVKKSSFFP YRWVLIQFGA
70 80 90 100 110 120
FIVLCGATHL INLWTFTTHT KTVAMVMTVA KVSTAVVSCA TALMLVHIIP DLLSVKTREL
130 140 150 160 170 180
FLKNKAEQLD REMGLIRTQE ETGRHVRMLT HEIRSTLDRH TILKTTLVEL GGTLGLEECA
190 200 210 220 230 240
LWMPSRSGSS LQLSHTLRHQ ITVGSTVSIN LPVVNQVFSS NRAIIIPHTS PLARIRPLAG
250 260 270 280 290 300
RYVPPEVAAV RVPLLHLSNF QINDWPELSA KSYAIMVLML PSDSARKWHV HELELVEVVA
310 320 330 340 350 360
DQVAVALSHA AILEESMRAR DLLMEQNVAL DLARREAEMA IRARNDFLAV MNHEMRTPMN
370 380 390 400 410 420
AIIALSSLLL ETELTPEQRL MVETVLKSSN LLATLINDVL DLSKLEDGSL ELEIKAFNLH
430 440 450 460 470 480
AVFKEVMSFI KPIAAIKRLS VSVMLAPDLP LCAIGDEKRL MQTILNISGN AVKFTKEGHI
490 500 510 520 530 540
TLVASVVKAD SLREFRTPDF HPTASDDNFY LKVQIKDTGC GISPQDLPQV FTKFAQSQPG
550 560 570 580 590 600
GNRGYSGSGL GLAICKRFVT LMGGHIWLDS EGTGRGCTVT FVIQLGICDN TNAYQQKLIP
610 620 630
LVWPSSGDAD FVGPVPNAPN EEKGQASLKS RYQRSI