A2X6X1

PR
Gene name
CDKG-1 (OsI_007814)
Protein name
Cyclin-dependent kinase G-1
Names
CDKG1
Species
Oryza sativa subsp indica (Rice)
KEGG Pathway
EC number
2.7.11.22: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

54-147 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

490-513 (Activation loop from InterPro)

Target domain

349-640 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for A2X6X1

Entry ID Method Resolution Chain Position Source
AF-A2X6X1-F1 Predicted AlphaFoldDB

No variants for A2X6X1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2X6X1

No associated diseases with A2X6X1

3 regional properties for A2X6X1

Type Name Position InterPro Accession
domain Protein kinase domain 349 - 640 IPR000719
active_site Serine/threonine-protein kinase, active site 469 - 481 IPR008271
domain Cyclin-dependent kinase 11/PITSLRE, catalytic domain 343 - 640 IPR045267

Functions

Description
EC Number 2.7.11.22 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
cyclin-dependent protein serine/threonine kinase activity Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
RNA polymerase II CTD heptapeptide repeat kinase activity Catalysis of the reaction: ATP + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = ADP + H+ + phosphorylated RNA polymerase II.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAGSHGGYR GYEVAREREH DVGVSRRSKE HYHHRHPSRH RDSERRRDGG RSGGRELSNG
70 80 90 100 110 120
YSHRRDSPRP PPRRRPSEGR TEDREPGEVS GGSGSERSGE RPMKTREPRE NGVTRVSKEE
130 140 150 160 170 180
AKMSPSKKRK QSPVIWDRNG SQRQARDPVR GIREVDAVVA EIIMHQSHSL PVMSSLSSIG
190 200 210 220 230 240
DGHSPMILDV SVDKVQEYEK NRIVDEEEEG YPTMRNILTS RWADAGDEEE NVFVPKKKKS
250 260 270 280 290 300
VSPVDSIERG STKKVTSPES GEVLVYNSVR SSSRSSDSGV LQGSANRDLE VEKGDNIDVE
310 320 330 340 350 360
KAADDDYPAG HLLDSDFEGE DCRSETPECT RSPRRCINML QGCRSVDEFE RLNTINEGTY
370 380 390 400 410 420
GVVFRVRDKR TGEIVALKKV KMEKEREGFP LTSLREMNIL LSFHHPSIVE VKEVVVGSND
430 440 450 460 470 480
RDIFMVMEYM EHDLKGVMET MKQPYSQSEV KCLMLQLLEG VKYLHDNWVL HRDLKTSNLL
490 500 510 520 530 540
LNNRGELKIC DFGLSRQYGS PLKPYTQLVV TLWYRAPELL LGAKDYSTAI DMWSLGCIMG
550 560 570 580 590 600
ELLSKGPLFN GKSEIDQLDK IFRTLGTPDE NIWPGYSKLP GATVKFGKQT HNRLRDKFRA
610 620 630 640 650 660
VSFTGGPMLS EAGFDLLNRL LTYDPEKRIS AEDALNHEWF RELPLPRSKD FMPTFPALNE
670 680 690
QDRRFKKHMK SPDPLEEQWM KEQGNNGDRG LFG