A2X0M1

PR
Gene name
MPK13 (BIMK2, BWMK2, MAPK2, MPK17-2)
Protein name
Mitogen-activated protein kinase 13
Names
MAP kinase 13, Benzothiadiazole-induced MAP kinase 2, MAP kinase 2, OsBIMK2, OsBWMK2, OsMAPK2, OsMPK17-2, Wound- and blast-induced MAPK 2
Species
Oryza sativa subsp indica (Rice)
KEGG Pathway
EC number
2.7.11.24: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

340-505 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

156-182 (Activation loop from InterPro)

Target domain

13-304 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for A2X0M1

Entry ID Method Resolution Chain Position Source
AF-A2X0M1-F1 Predicted AlphaFoldDB

No variants for A2X0M1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2X0M1

No associated diseases with A2X0M1

3 regional properties for A2X0M1

Type Name Position InterPro Accession
domain Protein kinase domain 13 - 304 IPR000719
conserved_site Mitogen-activated protein (MAP) kinase, conserved site 48 - 151 IPR003527
binding_site Protein kinase, ATP binding site 19 - 43 IPR017441

Functions

Description
EC Number 2.7.11.24 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
MAP kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEFFTEYGEA SQYQIQEVVG KGSYGVVAAA VDTHTGERVA IKKINDVFEH VSDAIRILRE
70 80 90 100 110 120
IKVLRLLRHP DIVVIKHIML PPTRREFRDI YVVFELMESD LHQVIEANHD LSPEHHRFFL
130 140 150 160 170 180
YQLLCALKYI HSANVFHRDL KPKNILANSD CKLKICDFGL ARVAFNDSPS TIFWTDYVAT
190 200 210 220 230 240
RWYRAPELCG SFFSKYTPAI DIWSIGCIFA EILTGRPLFP GRNVVHQLDL ITDLLGTPSS
250 260 270 280 290 300
ETLSRIRNEN ARGYLTGMQR KHPIPFSHKF HNADPLALRL LERLLAFDPK DRPTAEEALA
310 320 330 340 350 360
DPYFRGISKL SREPSRLPVS KFEFEFERRK LTKDDVREMI YREILEYHPQ MLQEYIRGGE
370 380 390 400 410 420
QISFLYPSGV DRFKRQFAHL EENYSRGERS TPLRRQHASL PRERVCSSVD SNNQDSDNEE
430 440 450 460 470 480
RRAISSIART MISPPRSQEK GKNRASAYPN GIINLNSNPK IYLKSASISA STCIIRGNKG
490 500
PKENGISEDM EEVVYELSDN VTRMLS