A2VDP6
Gene name |
NXPE3 (FAM55C) |
Protein name |
NXPE family member 3 |
Names |
Protein FAM55C |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:532838 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2VDP6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2VDP6-F1 | Predicted | AlphaFoldDB |
121 variants for A2VDP6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs447072802 | 28 | T>A | No | EVA | |
| rs468916635 | 28 | T>N | No | EVA | |
| rs480859279 | 29 | Q>R | No | EVA | |
| rs451105369 | 30 | V>I | No | EVA | |
| rs436967691 | 34 | D>A | No | EVA | |
| rs476548897 | 34 | D>H | No | EVA | |
| rs452239905 | 38 | A>S | No | EVA | |
| rs470776294 | 41 | T>R | No | EVA | |
| rs440860760 | 43 | I>R | No | EVA | |
| rs459297490 | 44 | D>A | No | EVA | |
| rs474394221 | 45 | S>R | No | EVA | |
| rs441596784 | 46 | G>C | No | EVA | |
| rs482612870 | 47 | G>V | No | EVA | |
| rs480094704 | 49 | F>L | No | EVA | |
| rs458301899 | 49 | F>V | No | EVA | |
| rs446930786 | 50 | V>G | No | EVA | |
| rs480608356 | 51 | S>C | No | EVA | |
| rs450957433 | 54 | V>G | No | EVA | |
| rs469363527 | 62 | Y>S | No | EVA | |
| rs452341178 | 65 | Y>* | No | EVA | |
| rs437042027 | 65 | Y>D | No | EVA | |
| rs437042027 | 65 | Y>N | No | EVA | |
| rs464329013 | 66 | E>* | No | EVA | |
| rs452870093 | 74 | E>G | No | EVA | |
| rs441558091 | 79 | D>V | No | EVA | |
| rs475413695 | 87 | W>G | No | EVA | |
| rs475413695 | 87 | W>R | No | EVA | |
| rs439857074 | 89 | E>G | No | EVA | |
| rs458394887 | 90 | P>A | No | EVA | |
| rs480036714 | 90 | P>R | No | EVA | |
| rs451018881 | 91 | D>E | No | EVA | |
| rs480671426 | 91 | D>G | No | EVA | |
| rs462231205 | 91 | D>N | No | EVA | |
| rs469374837 | 92 | V>G | No | EVA | |
| rs445910626 | 94 | P>T | No | EVA | |
| rs434545129 | 95 | V>A | No | EVA | |
| rs434545129 | 95 | V>G | No | EVA | |
| rs435208045 | 97 | F>C | No | EVA | |
| rs468217752 | 97 | F>L | No | EVA | |
| rs457002785 | 98 | L>F | No | EVA | |
| rs475411446 | 99 | K>E | No | EVA | |
| rs464021580 | 99 | K>R | No | EVA | |
| rs451960980 | 100 | S>G | No | EVA | |
| rs473740473 | 100 | S>R | No | EVA | |
| rs440748943 | 101 | T>N | No | EVA | |
| rs444510878 | 102 | D>E | No | EVA | |
| rs474418586 | 102 | D>G | No | EVA | |
| rs478226224 | 105 | S>F | No | EVA | |
| rs445240720 | 106 | S>R | No | EVA | |
| rs479473952 | 107 | Y>C | No | EVA | |
| rs458033957 | 107 | Y>N | No | EVA | |
| rs479473952 | 107 | Y>S | No | EVA | |
| rs446702475 | 108 | F>V | No | EVA | |
| rs468181121 | 109 | V>F | No | EVA | |
| rs435373640 | 109 | V>G | No | EVA | |
| rs450551459 | 110 | I>F | No | EVA | |
| rs469083023 | 112 | N>K | No | EVA | |
| rs432755745 | 113 | S>F | No | EVA | |
| rs434237219 | 117 | F>C | No | EVA | |
| rs876062666 | 118 | R>G | No | EVA | |
| rs474381509 | 118 | R>T | No | EVA | |
| rs876082953 | 119 | V>G | No | EVA | |
| rs444618175 | 120 | G>* | No | EVA | |
| rs463055896 | 122 | Q>E | No | EVA | |
| rs471918194 | 124 | E>V | No | EVA | |
| rs438898297 | 125 | V>A | No | EVA | |
| rs460456223 | 133 | Q>E | No | EVA | |
| rs478836040 | 135 | K>M | No | EVA | |
| rs446667490 | 141 | G>A | No | EVA | |
| rs461914933 | 143 | Y>H | No | EVA | |
| rs480199930 | 150 | S>P | No | EVA | |
| rs469210847 | 153 | L>R | No | EVA | |
| rs432830061 | 154 | Q>L | No | EVA | |
| rs444947691 | 157 | A>G | No | EVA | |
| rs433595997 | 158 | V>A | No | EVA | |
| rs433595997 | 158 | V>G | No | EVA | |
| rs466533379 | 158 | V>L | No | EVA | |
| rs474544951 | 160 | R>G | No | EVA | |
| rs438178901 | 160 | R>S | No | EVA | |
| rs456637125 | 161 | V>G | No | EVA | |
| rs472026542 | 162 | V>G | No | EVA | |
| rs454096997 | 163 | D>E | No | EVA | |
| rs438856369 | 163 | D>G | No | EVA | |
| rs472391674 | 164 | Y>H | No | EVA | |
| rs442808880 | 165 | Q>P | No | EVA | |
| rs461877814 | 166 | N>D | No | EVA | |
| rs480277758 | 166 | N>K | No | EVA | |
| rs462693379 | 168 | F>V | No | EVA | |
| rs444876461 | 169 | Y>* | No | EVA | |
| rs478059024 | 169 | Y>F | No | EVA | |
| rs478059024 | 169 | Y>S | No | EVA | |
| rs466696896 | 170 | K>Q | No | EVA | |
| rs448940637 | 171 | V>A | No | EVA | |
| rs448940637 | 171 | V>G | No | EVA | |
| rs456841976 | 174 | T>I | No | EVA | |
| rs438239310 | 174 | T>S | No | EVA | |
| rs454059984 | 186 | S>A | No | EVA | |
| rs442771965 | 188 | V>D | No | EVA | |
| rs876516278 | 189 | H>P | No | EVA | |
| rs454728493 | 190 | P>A | No | EVA | |
| rs476661777 | 198 | Q>R | No | EVA | |
| rs462892061 | 212 | S>R | No | EVA | |
| rs438662946 | 225 | C>G | No | EVA | |
| rs385915441 | 237 | N>K | No | EVA | |
| rs446198323 | 252 | P>R | No | EVA | |
| rs478664024 | 255 | L>P | No | EVA | |
| rs449004472 | 257 | C>R | No | EVA | |
| rs467339178 | 259 | S>R | No | EVA | |
| rs482688225 | 270 | K>N | No | EVA | |
| rs465708847 | 277 | E>D | No | EVA | |
| rs450286874 | 277 | E>K | No | EVA | |
| rs432577003 | 278 | N>H | No | EVA | |
| rs454217765 | 280 | F>S | No | EVA | |
| rs440205466 | 364 | I>L | No | EVA | |
| rs479684979 | 385 | S>R | No | EVA | |
| rs446488826 | 386 | P>T | No | EVA | |
| rs468335427 | 401 | I>S | No | EVA | |
| rs480268301 | 406 | R>S | No | EVA | |
| rs478577736 | 416 | T>N | No | EVA | |
| rs481645293 | 521 | V>I | No | EVA | |
| rs721677489 | 531 | Y>C | No | EVA |
No associated diseases with A2VDP6
No regional properties for A2VDP6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A2VDP6 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q969Y0 | NXPE3 | NXPE family member 3 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWINFVKLRL | FCCLLAVLMV | VVLVVNVTQV | EYLDRETASA | TFIDSGGQFV | SSQVIRISRN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PYCGYERQIL | SSRERLEEDS | LLAALQWQEP | DVGPVPFLKS | TDPSSSYFVI | LNSAAFFRVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SQLEVLVHVQ | DFQRKPKKYG | GDYLQARIHS | PKLQAGAVGR | VVDYQNGFYK | VFFTLLWPGQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKVSISLVHP | SEGIRVLQYL | QEKKPDRVYF | KSLFRSGRIS | ETTECNVCLP | GSLPLCNFTD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LYTGEPWFCF | KPKKLPCSSR | INHFKGGYLK | GLLTATENAF | FQSGVNIKMP | INSSGPDWVT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VIPRNIKETN | SLELSQGLGT | FPSGYYYKDQ | WRPRRFKMRQ | FNDPDNITEC | LQRKVVYLFG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DSTIRQWFEY | LTTFVPDLVE | FNLGSPKNVG | PFLAVDQKHN | ILLKYRCHGP | PIRFTTVFSS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DLRYVANELN | GIVGGKNTVV | AIAVWSHFST | FPLEVYIRRL | RNIRRAVVQL | LDRSPKTVVV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IRTANVQELG | PEISLFNSDW | YNFQLDTILR | KMFSGVGVYL | VDAWEMTLAH | YLPHKLHPDE |
| 550 | |||||
| VIVKNQVDMF | LSFVCPLET |