Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A2TJ54

Entry ID Method Resolution Chain Position Source
AF-A2TJ54-F1 Predicted AlphaFoldDB

No variants for A2TJ54

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2TJ54

1 associated diseases with A2TJ54

Without disease ID

No regional properties for A2TJ54

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A2TJ54

Functions

Description
EC Number 3.1.2.22 Thiolester hydrolases
Subcellular Localization
  • [Bis(monoacylglycero)phosphate synthase CLN5, secreted form]: Lysosome
  • ;
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
lysosome A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

1 GO annotations of molecular function

Name Definition
mannose binding Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.

4 GO annotations of biological process

Name Definition
glycosylation The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
positive regulation of GTP binding Any process that activates or increases the frequency, rate or extent of GTP binding.
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
signal peptide processing The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAQAGGAGAG AWGRRGAGAG AGPERAPWRW APALLWLAAA TAAAAAAGDP SRRQWPVPYK
70 80 90 100 110 120
RFSFRPEPDP YCQAKYTFCP TGSPIPVMKD DDVIEVFRLQ APVWEFKYGD LLGHLKIMHD
130 140 150 160 170 180
AIGFRSTLTE KNYTMEWYEL FQLGNCTFPH LRPEMNAPFW CNQGAACFFE GIDDNHWKEN
190 200 210 220 230 240
GTLVLVATIS GGMFNKMAKW VKQDNETGIY YETWTVQASP KKEAEKWFES YDCSKFVLRT
250 260 270 280 290 300
YEKLAELGAD FKKIETNYTR IFLYSGEPTY LGNETSVFGP TGNKTLALAI KKFYYPFKPH
310 320 330 340 350 360
LSTKEFLLSL LQIFDAVVIH REFYLFYNFE YWFLPMKSPF IKITYEEIPL PNRKNRTLSG
L