A2STI3

PR
Gene name
srp54
Protein name
Signal recognition particle 54 kDa protein
Names
SRP54
Species
Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
KEGG Pathway
mla:Mlab_1474
EC number
3.6.5.4: Acting on GTP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

312-386 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2STI3

Entry ID Method Resolution Chain Position Source
AF-A2STI3-F1 Predicted AlphaFoldDB

No variants for A2STI3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2STI3

No associated diseases with A2STI3

No regional properties for A2STI3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A2STI3

Functions

Description
EC Number 3.6.5.4 Acting on GTP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
  • The SRP-RNC complex is targeted to the cytoplasmic membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
signal recognition particle A complex of protein and RNA which facilitates translocation of proteins across membranes.

3 GO annotations of molecular function

Name Definition
7S RNA binding Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

1 GO annotations of biological process

Name Definition
SRP-dependent cotranslational protein targeting to membrane The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLDTLSNSL KDAMKKLAGK TVIDRAAVDE LVRDLQRALL SSDVNVKLVM ELSKQIKARS
70 80 90 100 110 120
LDEDLPKGIN AREHVLRIVY QELVNLVGKE AEFSLKPQKI LMAGLQGSGK TTTTGKLCRY
130 140 150 160 170 180
FQRKGLKVGA IGADNFRPGA YAQLETLCKK INVPSYGDPK EKDAVKIVKD GLAALKDVDV
190 200 210 220 230 240
IIVDTAGRHA LEDDLIDEIT QVNAYLNPDH RWLVIDAALG QAARDQAKRF HEAIGIDGVI
250 260 270 280 290 300
VTKMDGTAKG GGAMSAVAET QSGIVFIGNG ETIDDLERFD PNGFISRLLG MGDLKALVEK
310 320 330 340 350 360
AEESMNAEDV DVNAMLRGKF TLNDMYKQLE AVQKMGPLKQ VLSMLPMGNM NVPSDALEGT
370 380 390 400 410 420
ADKMKKFRII MDSMTPQELD EPALINTSRM IRVAKGSGSS VEEVRDLIKY YKMMQKTLKG
430 440
FRGNRMAMGK MMKQMQKGGM GPMGPM