A2SE11

PR
Gene name
hisE
Protein name
Phosphoribosyl-ATP pyrophosphatase
Names
PRA-PH
Species
Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1)
KEGG Pathway
mpt:Mpe_A0838
EC number
3.6.1.31: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

66-120 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2SE11

Entry ID Method Resolution Chain Position Source
AF-A2SE11-F1 Predicted AlphaFoldDB

No variants for A2SE11

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2SE11

No associated diseases with A2SE11

No regional properties for A2SE11

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A2SE11

Functions

Description
EC Number 3.6.1.31 In phosphorus-containing anhydrides
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
phosphoribosyl-ATP diphosphatase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+).

1 GO annotations of biological process

Name Definition
histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGDDTLARL AAVIESRRGG DPEASYVARL FHKGTDAILK KVGEEATEFV MAAKDGDRPK
70 80 90 100 110
IVAEAADLWF HAMVALAHFG LTPAQVLAEL ERREGQSGLE EFALRKVRGR EAESTKESGP