A2RT91

PR
Gene name
Ankar
Protein name
Ankyrin and armadillo repeat-containing protein
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:319695
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1325-1400 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2RT91

Entry ID Method Resolution Chain Position Source
AF-A2RT91-F1 Predicted AlphaFoldDB

88 variants for A2RT91

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388478076 28 Q>* No EVA
rs3388477361 42 E>* No EVA
rs3388477804 80 F>Y No EVA
rs3388478085 82 T>S No EVA
rs3390178804 89 V>C No EVA
rs3388478105 124 A>V No EVA
rs3388476849 143 V>G No EVA
rs3388477347 149 Q>H No EVA
rs3388477785 153 M>L No EVA
rs3388477715 160 G>* No EVA
rs3388476844 170 R>T No EVA
rs263129253 192 N>D No EVA
rs3388476842 203 V>A No EVA
rs3388476742 213 G>E No EVA
rs3388476405 232 E>Q No EVA
rs3388477157 244 M>L No EVA
rs224141882 252 V>I No EVA
rs3390187992 268 W>R No EVA
rs3388477329 312 G>E No EVA
rs249797687 313 M>V No EVA
rs226274572 317 K>R No EVA
rs265452819 331 R>K No EVA
rs3388477770 364 D>V No EVA
rs3388477199 367 C>S No EVA
rs1132226341 368 Q>E No EVA
rs3388478644 368 Q>H No EVA
rs3388476409 369 N>S No EVA
rs3388476408 393 V>I No EVA
rs51768524 411 A>V No EVA
rs3388477217 412 S>F No EVA
rs3388478610 419 A>V No EVA
rs3388477771 428 P>S No EVA
rs3390168813 438 Y>H No EVA
rs1134315471 475 T>S No EVA
rs1131878176 476 E>Q No EVA
rs1135111598 480 H>D No EVA
rs1134055120 482 Q>P No EVA
rs1132066299 489 L>S No EVA
rs3388476376 496 K>* No EVA
rs3388478115 501 G>VSDG* No EVA
rs3388477185 503 K>E No EVA
rs3388477238 504 S>F No EVA
rs3388476828 506 V>F No EVA
rs3388477862 509 G>D No EVA
rs3388476138 536 I>N No EVA
rs3388476470 542 L>M No EVA
rs3388477243 545 R>L No EVA
rs3388477767 625 F>S No EVA
rs3388477783 667 T>I No EVA
rs228554381 690 H>Q No EVA
rs3388477295 693 V>M No EVA
rs3388478092 715 W>L No EVA
rs3390167138 742 L>* No EVA
rs3390178711 756 T>S No EVA
rs3390167173 757 I>N No EVA
rs3390164890 758 P>R No EVA
rs3390164834 758 P>T No EVA
rs214434093 823 V>I No EVA
rs3388478576 883 L>F No EVA
rs252038106 908 D>N No EVA
rs1132952752 917 A>S No EVA
rs3390025514 957 E>F No EVA
rs45924668 1077 I>V No EVA
rs3388478648 1124 V>I No EVA
rs3388477370 1125 L>S No EVA
rs3388476777 1161 G>A No EVA
rs3388476892 1162 Y>C No EVA
rs3388478744 1173 F>C No EVA
rs228760326 1197 V>I No EVA
rs3388477336 1202 A>T No EVA
rs3388477809 1206 F>L No EVA
rs3388476207 1213 K>* No EVA
rs51817549 1214 A>T No EVA
rs48386843 1219 E>D No EVA
rs231616541 1219 E>G No EVA
rs3388476375 1247 G>C No EVA
rs3390178797 1266 S>P No EVA
rs3390087090 1267 L>V No EVA
rs3388477142 1278 Y>F No EVA
rs3388477063 1280 R>K No EVA
rs3390087078 1344 G>E No EVA
rs3390166483 1345 L>V No EVA
rs3388477029 1383 T>I No EVA
rs3388477029 1383 T>N No EVA
rs3388476450 1398 T>I No EVA
rs3388476799 1403 I>V No EVA
rs216961846 1412 S>P No EVA
rs3388477092 1465 Q>* No EVA

No associated diseases with A2RT91

12 regional properties for A2RT91

Type Name Position InterPro Accession
repeat Armadillo 744 - 825 IPR000225-1
repeat Armadillo 827 - 865 IPR000225-2
repeat Armadillo 867 - 907 IPR000225-3
repeat Armadillo 909 - 949 IPR000225-4
repeat Armadillo 1034 - 1077 IPR000225-5
repeat Armadillo 1084 - 1123 IPR000225-6
repeat Armadillo 1257 - 1297 IPR000225-7
repeat Ankyrin repeat 532 - 561 IPR002110-1
repeat Ankyrin repeat 582 - 614 IPR002110-2
repeat Ankyrin repeat 615 - 644 IPR002110-3
repeat Ankyrin repeat 651 - 683 IPR002110-4
repeat Ankyrin repeat 684 - 714 IPR002110-5

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRIVKKGIV KIDQEQDEET FRENLAVQRN ASAFFEKYDR TEVQELLTTT LVSWLAAKDD
70 80 90 100 110 120
ARSQLETPCG LMSQMNNAGF STAILLTPVD PTALLDYREV HQILRELAIG IYCLNQIPSI
130 140 150 160 170 180
SLEANFDQSS SCQLPPAYYD TRVGQILIQI DYMLKALWHG IYMPKEKRAR FSELWRTIMD
190 200 210 220 230 240
IDLDGKPQTT KNVFSEFSSA GLVDITNDPD FNGIYDEDMN EDPTYEPNSP EEKAVFMKYA
250 260 270 280 290 300
ESIMMKLTFS TVQIQQHENI FIFETAYWLS NAIKYNQDYL DICTYQRLQK RLYLQKKVIQ
310 320 330 340 350 360
KHFEKKKEIR RGMGYLKLIC FLIPFLLSLK RKMKVPYLNS LLPPFSDDKV KTERELPPFI
370 380 390 400 410 420
YGRDFKCQNF DYKQHQYFHV HGGIEFDIST HPVESALDEF KKNVEKIWEC ASSASAEDAG
430 440 450 460 470 480
YKEVYPIPVM ELNGKSYYVI HFELEIFYQQ LYKTQWWVAI NETVNNLKVK RLPLTEDQLH
490 500 510 520 530 540
EQFKKKFGLK KAMKCKSIPF GVKSAVERGL SAVFYTFSRK TSSSTINVSD EAGYAIFHHA
550 560 570 580 590 600
ALHNRVSVIC QLWSANFNVN QRRFIMFSQA DSSKVDMKKE RNGPTPLHLA AQACSLEATI
610 620 630 640 650 660
CLLCFKADYT LTEKRGWMPI HFAAFYDNIC ILIALCRKDP SLLEAEATAE NQCTPLLLAA
670 680 690 700 710 720
TSGALDTIQY LFSLGANWRK TDTKGNNIIH LSVLAFHTEV LKYIIELNIP ELPVWETLVE
730 740 750 760 770 780
MLQCESSKRR MMAVMSLEVI CLANDRYWQC ILDAGTIPAL VNLLKSPQIK LQYKTVGLLS
790 800 810 820 830 840
NISTHVSIVH AIVEAGGIPA VINLLTSDEP ELHSRCAIIL YDVAKCENKD VIAKYSGIPA
850 860 870 880 890 900
LINLLSLNKE SVLVNVMNCI RVLCMGNESN QQSMKDNNGI QYLIQFLSSD SDVLKALSSA
910 920 930 940 950 960
TIAEVARDNK EVQDAIAKEG AIPPLVTLFK GKQLSVQVKG AMAVESLANC NPLIQKEFLE
970 980 990 1000 1010 1020
RELTKDLLKL LQAFQIDVKE QGAIALWALA GQTLKQQKYM AEQIGYNLII SMLLSPSAKM
1030 1040 1050 1060 1070 1080
QYVGGEAVIA LSKDSRMHQN QICEGKGIAP LVRLLRINKI PEGTLLSVIR AVGSICIGVA
1090 1100 1110 1120 1130 1140
HTSNPMSQQF VVEENALPVL IQLLRNHPSI NIRVEVAFSL ACIVLGNNSL KKELQNDEGF
1150 1160 1170 1180 1190 1200
EYSDVLYLLH SKDKEVCLKA GYALTLFAFN DRFQQHLILE TGLITVSIFE PFLQSSVETE
1210 1220 1230 1240 1250 1260
RAMAAFQIII LAKAIIDVEH VTLYGRGIQI LADSLNSVHA PTIALTGNII ASLAHSRAGI
1270 1280 1290 1300 1310 1320
PEAFVSLGTV QRLCYHLYAR SEEVRTACSC ALGYLTYNAH AFRLLLTECR NKPNQFLRIT
1330 1340 1350 1360 1370 1380
NNISKDAKIN PAFLKEFQLQ QRMGLPSLSL ERNGGPPVIP VFKKGKEHRQ KTRPKIQPRD
1390 1400 1410 1420 1430 1440
SLTLLPPVTN VKELFRTTHK ANISHNTFSF PSGVSSDIIN VSRPRIAFLN KLGKDEQKAN
1450 1460
PDPPAFLNKL GKDEQNANPD PAESQ