A2RSJ4
PR
Gene name |
Uhrf1bp1l |
Protein name |
UHRF1-binding protein 1-like |
Names |
Syntaxin-6 Habc-interacting protein of 164 kDa |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:75089 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2RSJ4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2RSJ4-F1 | Predicted | AlphaFoldDB |
78 variants for A2RSJ4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389133220 | 139 | K>Q | No | EVA | |
| rs3389123366 | 156 | N>K | No | EVA | |
| rs3389088774 | 228 | N>H | No | EVA | |
| rs3389126804 | 231 | A>S | No | EVA | |
| rs3389099631 | 265 | E>* | No | EVA | |
| rs3389131354 | 268 | T>K | No | EVA | |
| rs3389133207 | 275 | A>T | No | EVA | |
| rs3389122739 | 285 | T>S | No | EVA | |
| rs3389121164 | 316 | K>T | No | EVA | |
| rs48592428 | 346 | V>I | No | EVA | |
| rs3401443519 | 370 | D>V | No | EVA | |
| rs260178010 | 417 | K>T | No | EVA | |
| rs3389122791 | 451 | A>V | No | EVA | |
| rs3401065581 | 460 | V>D | No | EVA | |
| rs3389099555 | 478 | S>P | No | EVA | |
| rs3389121097 | 481 | K>I | No | EVA | |
| rs3401704528 | 487 | N>I | No | EVA | |
| rs3401348144 | 526 | L>Q | No | EVA | |
| rs3389123330 | 570 | H>D | No | EVA | |
| rs3401544681 | 583 | V>F | No | EVA | |
| rs3389121081 | 622 | D>V | No | EVA | |
| rs3389122797 | 645 | K>Q | No | EVA | |
| rs3389118142 | 647 | C>S | No | EVA | |
| rs3389109955 | 648 | D>H | No | EVA | |
| rs3389126803 | 656 | I>S | No | EVA | |
| rs3389088778 | 661 | A>V | No | EVA | |
| rs3389133203 | 667 | K>T | No | EVA | |
| rs3389109933 | 678 | P>H | No | EVA | |
| rs3389120962 | 701 | F>C | No | EVA | |
| rs3389122763 | 733 | R>G | No | EVA | |
| rs224395508 | 733 | R>S | No | EVA | |
| rs3389118117 | 735 | A>T | No | EVA | |
| rs3389120891 | 760 | A>V | No | EVA | |
| rs3389099596 | 789 | S>L | No | EVA | |
| rs3389116080 | 827 | L>P | No | EVA | |
| rs3389121161 | 838 | D>N | No | EVA | |
| rs30344579 | 848 | I>T | No | EVA | |
| rs3389088800 | 851 | P>L | No | EVA | |
| rs3389120888 | 858 | C>Y | No | EVA | |
| rs30344581 | 861 | I>V | No | EVA | |
| rs3389118127 | 941 | P>H | No | EVA | |
| rs3389099587 | 969 | K>I | No | EVA | |
| rs3400804198 | 974 | I>R | No | EVA | |
| rs3389131342 | 977 | D>V | No | EVA | |
| rs3389063284 | 977 | D>Y | No | EVA | |
| rs30345405 | 983 | S>A | No | EVA | |
| rs3389109953 | 986 | S>T | No | EVA | |
| rs3389131393 | 999 | K>E | No | EVA | |
| rs47515767 | 1017 | T>A | No | EVA | |
| rs47515767 | 1017 | T>S | No | EVA | |
| rs217331631 | 1026 | N>S | No | EVA | |
| rs3389088777 | 1030 | P>R | No | EVA | |
| rs3389126877 | 1036 | G>D | No | EVA | |
| rs3389088781 | 1037 | K>N | No | EVA | |
| rs30345407 | 1056 | A>V | No | EVA | |
| rs259571347 | 1062 | P>R | No | EVA | |
| rs216279067 | 1071 | P>L | No | EVA | |
| rs3389122762 | 1094 | A>P | No | EVA | |
| rs3389095679 | 1097 | S>T | No | EVA | |
| rs3389088753 | 1157 | N>K | No | EVA | |
| rs29356479 | 1161 | N>D | No | EVA | |
| rs29377012 | 1164 | T>A | No | EVA | |
| rs29383909 | 1171 | E>D | No | EVA | |
| rs3389124894 | 1175 | T>A | No | EVA | |
| rs3389095620 | 1180 | T>M | No | EVA | |
| rs3389120971 | 1207 | E>K | No | EVA | |
| rs30342658 | 1219 | T>M | No | EVA | |
| rs3389133182 | 1256 | R>G | No | EVA | |
| rs3389122766 | 1266 | H>L | No | EVA | |
| rs3389124961 | 1283 | F>L | No | EVA | |
| rs30343473 | 1328 | G>S | No | EVA | |
| rs3389123342 | 1329 | S>I | No | EVA | |
| rs3389131339 | 1337 | P>L | No | EVA | |
| rs3389126867 | 1357 | I>V | No | EVA | |
| rs3389124887 | 1380 | R>W | No | EVA | |
| rs3389109871 | 1398 | Q>E | No | EVA | |
| rs3389124925 | 1411 | N>H | No | EVA | |
| rs3389118133 | 1414 | D>H | No | EVA |
No associated diseases with A2RSJ4
1 regional properties for A2RSJ4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Vacuolar protein sorting-associated protein 13-like, N-terminal domain | 2 - 94 | IPR026854 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| early endosome | A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GARP complex binding | Binding to a GARP complex. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A0JNW5 | UHRF1BP1L | UHRF1-binding protein 1-like | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGIIKKQIL | KHLSRFTKNL | SPDKINLSTL | KGEGELKNLE | LDEEVLQNML | DLPTWLAISK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VFCNKASIRI | PWTKLKTQPI | CLSLDKVIME | MSTCEEPRAP | NGPSPIATAS | GQSEYGFAEK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VVEGITVSVN | SIVIRIGAKA | FNASFELSQL | RIYSVNAQWE | HGDLRFTRIQ | DPQRGEVLTF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEINWQMIRI | EADATQSSHL | EIMCAPVRLI | TNQSKIRVTL | KRRLKDCNVI | ATKLVLILDD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLWVLTDSQL | KAMVQYAKSL | SEAIEKSTEQ | RKSMAPEPTQ | SSTVTSSAQH | VKTPQAANAP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DLSDAIVKLF | NDFDVKETSH | HLVISHLDLH | ICDDIHAKEK | ESNRRVSGGA | MQLSFTQLTI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DYYPYHKAGD | SCSHWMYFSD | ATKTKNGWAN | ELLHEFECNV | EMLKQAMKDR | NLGSPPKSPT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| HASPQHTQTE | KDSTLKGTPK | TPSVLPQPSK | AKLMSSSVVV | RLADFNIYQV | STAEQCRSSP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KSMISCNKKS | LYLPQEMSAI | YIEFTEYYYP | DGKDFPIPSP | NLYSQLNALQ | FTVDERSILW |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LNQFLLDLKQ | SLNQFMAVYK | LNDSSKSDEH | VDIRVDGLML | KFVIPSEVKA | GCHQDQPHTV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SIQSSEMIAT | NTRHCPNCRH | SDLEALCQDF | KECDFFSKTY | TRFPKSCDSF | NLLHPIFQRH |
| 670 | 680 | 690 | 700 | 710 | 720 |
| AHEQDTKMHE | VYKGNIIPKL | NKNTLKTSAA | TDVWAVYFSQ | FWIDYEGMKS | GKGRPVSFVD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| AFPLSIWICQ | PTRYAELQKE | FQTCDQVTLN | TSQSESSDLA | GRMKRKKLLK | EYYSTESEPL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| TNGGQRPSSD | TFLRFSSSSS | DADVHVLVRV | HKHVSMQINH | YQYLLLLFIH | ESLVLLSDTL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RRDVEAVIGS | PASQTSVCVG | ILLRSAELAL | LLHPVNPTSA | LRSPASESGS | PLLPDFLPAE |
| 910 | 920 | 930 | 940 | 950 | 960 |
| NGGFLSSKRK | QGGSGIHRIR | NATLNHMSDN | RSMSVDLSHA | PLKDPLLFKS | ASDTNLQKGT |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| SFLDYLSDKH | LGKISEDESS | GLSHKSGSGE | MTSEGSHTKD | VASTDSDSVL | NYRDGSTRLS |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| LDDDGNHNPP | SNPVTGKGID | AIHSIFRAED | FLPEAASLSE | NPESSKEEAP | PARAPKSQTS |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| LSAKSKERCP | PSPAPLSVSY | KNMKRSASQV | SLDTLSLDSM | VLEEQAESDG | SDSHVLLGKA |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| MKRNSNTSCQ | SPAESVNTSA | NTQTCGEASP | EAVSTNSEGT | QENRDDLMSV | VVFRITGVNG |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| EIDIRGEDTE | VCLQVNQVTP | SQLGNVSLRH | YLGNRPVGSD | QKAIIHPKSS | PEISLRFESG |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| PGAVVHSLLA | EKNGFLQCHI | ENFTTEFLTS | SLLNIQHFLE | DETVATVMPM | KIQVSNTKIN |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| LKDDSPRGST | VSLQPSPVTV | HIDRLVVERS | DDGSFHIRDS | HLFNTGTDFK | DGASSDSVVR |
| 1390 | 1400 | 1410 | 1420 | 1430 | 1440 |
| TRGMCDVRMH | SSVTQATQTS | PEVPLPSQSA | NFLDITREQL | MEENECLRQR | LAQAKMELAE |
| 1450 | |||||
| AHSARDELLH | QMKRMGL |