A2RFN2

PR
Gene name
prfB
Protein name
Peptide chain release factor 2
Names
RF-2
Species
Streptococcus pyogenes serotype M5 (strain Manfredo)
KEGG Pathway
spf:SpyM51333
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

269-339 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2RFN2

Entry ID Method Resolution Chain Position Source
AF-A2RFN2-F1 Predicted AlphaFoldDB

No variants for A2RFN2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2RFN2

No associated diseases with A2RFN2

2 regional properties for A2RFN2

Type Name Position InterPro Accession
domain Peptide chain release factor class I 226 - 335 IPR000352
domain Peptide chain release factor 29 - 217 IPR005139

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
translation release factor activity, codon specific A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEVAEIRQKI VENKEKLTSF RRSLDLDRLE EEIALLENHM TEPDFWNDNI AAQKTSQELN
70 80 90 100 110 120
ELKGKYDTFH NMQELSDETE LLLEMLDEDD SLKEELEENL MQLDKIMGAY EMTLLLSEPY
130 140 150 160 170 180
DHNNAILEIH PGSGGTEAQD WGDLLLRMYT RFGNANGFKV EVLDYQAGDE AGIKSVTLSF
190 200 210 220 230 240
EGPNAYGLLK SEMGVHRLVR ISPFDSAKRR HTSFASVEVM PELDNTIEVE VRDDDIKMDT
250 260 270 280 290 300
FRSGGAGGQN VNKVSTGVRL THIPTGIVVS STVDRTQYGN RDRAMKMLQA KLYQLEQEKK
310 320 330 340 350 360
AQEVDALKGD KKEITWGSQI RSYVFTPYTM VKDHRTNFEL AQVDKVMDGE INGFIDAYLK
WRIED