A2RAL4

PR
Gene name
bglA (bgl1, An18g03570)
Protein name
Probable beta-glucosidase A
Names
Beta-D-glucoside glucohydrolase A, Cellobiase A, Gentiobiase A
Species
Aspergillus niger (strain CBS 51388 / FGSC A1513)
KEGG Pathway
ang:ANI_1_456164
EC number
3.2.1.21: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

642-775 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2RAL4

Entry ID Method Resolution Chain Position Source
AF-A2RAL4-F1 Predicted AlphaFoldDB

No variants for A2RAL4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2RAL4

No associated diseases with A2RAL4

4 regional properties for A2RAL4

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 3, N-terminal 82 - 338 IPR001764
domain Glycoside hydrolase family 3 C-terminal domain 400 - 654 IPR002772
active_site Glycoside hydrolase, family 3, active site 266 - 283 IPR019800
domain Fibronectin type III-like domain 779 - 847 IPR026891

Functions

Description
EC Number 3.2.1.21 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

3 GO annotations of molecular function

Name Definition
beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
glucosidase activity Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.
scopolin beta-glucosidase activity Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.

2 GO annotations of biological process

Name Definition
cellular carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
cellulose catabolic process The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRFTSIEAVA LTAVSLASAD ELAYSPPYYP SPWANGQGDW AEAYQRAVDI VSQMTLAEKV
70 80 90 100 110 120
NLTTGTGWEL ELCVGQTGGV PRLGIPGMCA QDSPLGVRDS DYNSAFPAGV NVAATWDKNL
130 140 150 160 170 180
AYLRGQAMGQ EFSDKGADIQ LGPAAGPLGR SPDGGRNWEG FSPDPALSGV LFAETIKGIQ
190 200 210 220 230 240
DAGVVATAKH YIAYEQEHFR QAPEAQGYGF NITESGSANL DDKTMHELYL WPFADAIRAG
250 260 270 280 290 300
AGAVMCSYNQ INNSYGCQNS YTLNKLLKAE LGFQGFVMSD WAAHHAGVSG ALAGLDMSMP
310 320 330 340 350 360
GDVDYDSGTS YWGTNLTISV LNGTVPQWRV DDMAVRIMAA YYKVGRDRLW TPPNFSSWTR
370 380 390 400 410 420
DEYGFKYYYV SEGPYEKVNQ FVNVQRNHSE LIRRIGADST VLLKNDGALP LTGKERLVAL
430 440 450 460 470 480
IGEDAGSNPY GANGCSDRGC DNGTLAMGWG SGTANFPYLV TPEQAISNEV LKNKNGVFTA
490 500 510 520 530 540
TDNWAIDQIE ALAKTASVSL VFVNADSGEG YINVDGNLGD RRNLTLWRNG DNVIKAAASN
550 560 570 580 590 600
CNNTIVIIHS VGPVLVNEWY DNPNVTAILW GGLPGQESGN SLADVLYGRV NPGAKSPFTW
610 620 630 640 650 660
GKTREAYQDY LYTEPNNGNG APQEDFVEGV FIDYRGFDKR NETPIYEFGY GLSYTTFNYS
670 680 690 700 710 720
NLQVEVLSAP AYEPASGETE AAPTFGEVGN ASDYLYPDGL QRITKFIYPW LNSTDLEASS
730 740 750 760 770 780
GDASYGQDAS DYLPEGATDG SAQPILPAGG GAGGNPRLYD ELIRVSVTIK NTGKVAGDEV
790 800 810 820 830 840
PQLYVSLGGP NEPKIVLRQF ERITLQPSKE TQWSTTLTRR DLANWNVETQ DWEITSYPKM
850
VFAGSSSRKL PLRASLPTVH