A2QWW0

PR
Gene name
mak5 (An11g06650)
Protein name
ATP-dependent RNA helicase mak5
Names
Species
Aspergillus niger (strain CBS 51388 / FGSC A1513)
KEGG Pathway
ang:ANI_1_876094
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-197 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2QWW0

Entry ID Method Resolution Chain Position Source
AF-A2QWW0-F1 Predicted AlphaFoldDB

No variants for A2QWW0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2QWW0

No associated diseases with A2QWW0

2 regional properties for A2QWW0

Type Name Position InterPro Accession
domain Translation initiation factor 3, N-terminal 19 - 88 IPR019814
domain Translation initiation factor 3, C-terminal 95 - 180 IPR019815

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGQKRQRGSK SADLQAKKRK KDVSAVEDGE DALVTVNDLN WKEVALPDRL EDAGGFFGLE
70 80 90 100 110 120
EIDGVEVIKG GSEGLRFKAA HGKPKKSILK KKAPEEEEPK FDDDEWSGFS DNEVTEKKDT
130 140 150 160 170 180
APKEDQKDEQ EADKPTAEEK KKAKKDRQAE QKKAKKEAKQ KTTPNQEDKS IKPGLSFAAL
190 200 210 220 230 240
QDEEDDDGVD VSAWESLGLS PEILTSLSKM KFTTPTLVQK SCIPQILDGH DVIGKASTGS
250 260 270 280 290 300
GKTLAFGIPI LEHYLEKRRQ DLRAGKEEKK KDTAPIALIM SPTRELAHQL AKHIGELALH
310 320 330 340 350 360
APGSNARIAL LTGGLSVQKQ QRVLAGADIV IGTPGRVWEV LSSGQGLIRK MSEIKFLVID
370 380 390 400 410 420
EADRLLSEGH FKEAEEILGA LDRVEEGNFG GEESEDEEKE DARSERQTLV FSATFHRDLQ
430 440 450 460 470 480
QKLAGKARWT GGDIMSNKES MEYLLQKLKF REEKPKFIDV NPVSQMAEGL KEGIVECGAM
490 500 510 520 530 540
EKDLYLYTLL LYNPKHRTLV FTNSISAVRR LTQLLQNLGL PALALHSSMA QKARLRSVER
550 560 570 580 590 600
FSSPTSDPSS ILVATDVAAR GLDIKGIDFV IHYHAPRAAD TYVHRSGRTA RAGASGKSVI
610 620 630 640 650 660
ICAPEEMVGV VRLAAKVHAN MANGKKLPLE SLELDRRVVL RVRQRVDLAA KITDSNIAKE
670 680 690 700 710 720
KISAEDNWLQ KAAEDLGVEY DSEEFESAQG RGRGRGRGRQ ERQRKAGEVT KNELAAMRAE
730 740 750 760
LKHLLSQRVN VGVSERYLTS GRVDIEALLR GEGNNSFLGQ VDPLDF