Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2QLJ9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2QLJ9-F1 | Predicted | AlphaFoldDB |
No variants for A2QLJ9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A2QLJ9 | |||||
No associated diseases with A2QLJ9
No regional properties for A2QLJ9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A2QLJ9 | |||
Functions
7 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle membrane | The lipid bilayer surrounding a cytoplasmic vesicle. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| phagophore | A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle. |
| phagophore assembly site membrane | A cellular membrane associated with the phagophore assembly site. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| phospholipid scramblase activity | Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| autophagy of mitochondrion | The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions. |
| late nucleophagy | A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM. |
| piecemeal microautophagy of the nucleus | Degradation of a cell nucleus by lysosomal microautophagy. |
| protein localization to phagophore assembly site | Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). |
| reticulophagy | The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMTSNILSRF | LPPNGSPSVY | ETIRQHDNHS | DASDVEERAG | MAFEDEHGDR | FSDRELEDAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ADAGRDDSPG | PSEPFLPRSP | PTKRDEGGFL | KAGSRRRKFS | RSGRIHAASP | RHKFDDSDDD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VPPSLLVEGD | QDDDDVLRSK | LPPPPRSIDP | PNVEPPPRPS | PRDDRVHWEA | ARDRLPLHDT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NRRAHHASLW | SAGYPNLALV | DPKEKALWMW | ANVENLDNFL | KEVYTYFLGN | GIWSILLNRV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSLLTFAFVV | GFSIFLTNCI | DYHKVRGSRT | LDDILIQKCT | KQMSMSATFL | LWLLSFFWIG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KAFQYLLDIR | RLKHMHDFYH | YLLGISDAEI | QSISWQEVVS | RLMTLRDSNP | ATAGAVSAKH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RKFMGSQSKQ | RMDAHDIANR | LMRKENYLIA | LINKDILDLT | LPIPFLRNRQ | LFSRTLEWNI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NLCIMDYVFN | EQGQVRTLFL | KDTHRRALSE | GLRRRFMFAG | IMNIFVAPFI | VVYFMMHYFF |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RYFNEYKKNP | SQIGSRQYTP | LAEWKFREFN | ELWHLFERRV | NMSYPFASRY | VDQFPKDKMV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| QFAGFVAFVS | GALASVLALA | SVVDPELFLG | FEITHDRTVL | FYLGVFGSIW | AVAQGLVPEE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TNVFDPEYAL | LEVINFTHYF | PGHWKGRLHS | DDVRKDFAVL | YQMKIVIFLE | EILSMIFTPF |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ILWFSLPKCS | DRLIDFFREF | TVHVDGMGYL | CSFAVFDFKK | GTNVISQGDT | GRRDAARQDL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RADYFSTKDG | KMLASYYGFL | DNYGANPRSG | HPSTKRQFHP | PPTFPTLGSP | SAIEMGNFGD |
| 790 | 800 | 810 | 820 | 830 | 840 |
| RPAAAGLMGQ | QSTYGAAPRF | GPAGMGDHLS | PAPSMLLDPH | HQPSASGFRS | THRANPYPRY |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RASRPPPTIS | DPIEDEDPPA | GKGRSAVKSS | PGVGSSGGGI | GTSDSNLGES | WRMNLVGDEV |
| 910 | 920 | 930 | 940 | ||
| EEEDEGGENV | DTLAGGGGVL | GLIQQFQKVN | QDNRGRTTVG | I |