A2QGA1

PR
Gene name
An03g02430
Protein name
Mannitol 2-dehydrogenase
Names
M2DH, MDH
Species
Aspergillus niger (strain CBS 51388 / FGSC A1513)
KEGG Pathway
EC number
1.1.1.67: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2QGA1

Entry ID Method Resolution Chain Position Source
AF-A2QGA1-F1 Predicted AlphaFoldDB

No variants for A2QGA1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2QGA1

No associated diseases with A2QGA1

2 regional properties for A2QGA1

Type Name Position InterPro Accession
domain Mannitol dehydrogenase, C-terminal 217 - 461 IPR013118
domain Mannitol dehydrogenase, N-terminal 36 - 189 IPR013131

Functions

Description
EC Number 1.1.1.67 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
mannitol 2-dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGPLKLNTAN LSQIVAAGAG RVKVPTYRRG PALKEGIVHV GVGGFHRAHL AVYVDQLMQN
70 80 90 100 110 120
HGVTDYAICG VGLQPFDSAM RDALSSQDNL YTVIERSAKG SFANVIGSIN SYLFAPDDRE
130 140 150 160 170 180
AVIAKMAHPD TRIVSLTITE SGYYYNENTH ELQSEHPDIQ FDLDPANEKT PRTTFGFLYA
190 200 210 220 230 240
ALARRHQQEE WFHHPSHARV FRPSPHPEVA QWITDKGAFP NAMVDRITPQ TSPADKESLA
250 260 270 280 290 300
NTMGIEDSWP VVTEPFMQWV IEDQFSDGRP PFEKVGVQVV KDVHAVEEFE KHKLRLLNGS
310 320 330 340 350 360
HSAIGYPGQM AGFNYVHEVL ENPDFNKFVW QMMQEEVKPS LPEIPGVDID QYCKTLMERF
370 380 390 400 410 420
SNPTIMDQLP RICLNASGKI PQFIMPSIAE AIWVKGPLRR LCFVAAAWFR YINGVDDQGN
430 440 450 460 470 480
TFTVDDPMRE ELQAKARAGG TKPSELLSIT SLFGDDLRND KRFMQEITNA MEDIARDGIL
KTLPKYID