A2Q9T6

PR
Gene name
has1 (An01g09040)
Protein name
ATP-dependent RNA helicase has1
Names
Species
Aspergillus niger (strain CBS 51388 / FGSC A1513)
KEGG Pathway
ang:ANI_1_1224014
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-114 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2Q9T6

Entry ID Method Resolution Chain Position Source
AF-A2Q9T6-F1 Predicted AlphaFoldDB

No variants for A2Q9T6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2Q9T6

No associated diseases with A2Q9T6

No regional properties for A2Q9T6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A2Q9T6

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPIPVDTAKS INKKRKRKHG ARAATDADDA SPKPAVENGE TTEVTETPTE KKSKKKAAKE
70 80 90 100 110 120
SEKEEKPKKR KVDDSSNEDE NDSEEEVREA DPEDEDDNEG KEDGNGADLP SLDAVRLPQT
130 140 150 160 170 180
DGEPKKFTEL NLSEKTMKGI QDMGFETMTE IQQRTIPPLL AGRDVLGAAK TGSGKTLSFL
190 200 210 220 230 240
IPAVEMLSAL RFKPRNGTGV LVVSPTRELA LQIFGVAREL MAHHSQTYGI VIGGANRRAE
250 260 270 280 290 300
AEKLTKGVNL LIATPGRLLD HLQNTPGFVF KNLKTLVIDE ADRILEVGFE DEMRQIVKIL
310 320 330 340 350 360
PSEERQTMLF SATQTTKVED LARISLRPGP LYINVDHRKE HSTVEGLEQG YVICEADKRF
370 380 390 400 410 420
LLLFSFLKRN LKKKIIVFFS SCNCVKYHAE LLNYIDLPVL ELHGKQKQQK RTNTFFEFCN
430 440 450 460 470 480
AKQGTLICTD VAARGLDIPA VDWIIQFDPP DDTRDYVHRV GRTARGVNGK GRSLMFLQPS
490 500 510 520 530 540
EVGFLKHLKE ARVPVVEFDF PANKIVNVQS QLEKLIGQNY YLNKSAKEGY RAYLQAYASH
550 560 570 580 590 600
SLRSVFDVHK LDLVKIAKGF GFSTPPRIDI QLGSSLSRDK KQQQQGRRNY GSQPKGLKFK
RKHEDD