A2Q8L1

PR
Gene name
sec23 (An01g04730)
Protein name
Protein transport protein sec23
Names
Species
Aspergillus niger (strain CBS 51388 / FGSC A1513)
KEGG Pathway
ang:ANI_1_612014
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

275-346 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2Q8L1

Entry ID Method Resolution Chain Position Source
AF-A2Q8L1-F1 Predicted AlphaFoldDB

No variants for A2Q8L1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2Q8L1

No associated diseases with A2Q8L1

6 regional properties for A2Q8L1

Type Name Position InterPro Accession
domain Zinc finger, Sec23/Sec24-type 60 - 99 IPR006895
domain Sec23/Sec24, trunk domain 127 - 391 IPR006896
domain Sec23/Sec24, helical domain 520 - 618 IPR006900
domain Gelsolin-like domain 635 - 721 IPR007123
domain Sec23/Sec24 beta-sandwich 402 - 506 IPR012990
domain Sec23, C-terminal 612 - 728 IPR037550

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
COPII vesicle coat One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

1 GO annotations of molecular function

Name Definition
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
COPII-coated vesicle budding The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDYEALKDQW SDVEDRDGIR LSWNTFPSSR MEASRLVVPI GAVYTPLKEK PDSPLLQYEP
70 80 90 100 110 120
VTCKAPCRAV LNPYANVDVR ARIWICPFCL MRNPLPPHYK DITESTIPPE LHPMSTTIEY
130 140 150 160 170 180
QLARPAPAPP IFVYVVDTCQ DDDSLKALKD SLIMSLSLLP VNALVGLITY GTMAQVHELG
190 200 210 220 230 240
YTECAKSYVF RGSKEYAAKQ VQEMLGLASG LRPNMPQQPA RPPLGPAARF LLPVQQAEFQ
250 260 270 280 290 300
ITNVLEQLQR DPWPVANDKR PLRCTGVALS VAVGLLETSF QNAGGRIMVF TSGPATEGPG
310 320 330 340 350 360
HVVGPELKEP IRSHHDIDRD NIKYYKKAVK FYDNMAKRAA NNGHIVDVFA GCLDQVGMLE
370 380 390 400 410 420
MKNLANYTGG HILLTDSFTS SQFKQSFVRI FDKDAKDNLL MGFNASLEVL TTKELKVTGL
430 440 450 460 470 480
IGHAVSLNKK SSSVGETECG IGNTCAWKMC GIDPASSYGV YFEIANQGGP AAVQPGPQRG
490 500 510 520 530 540
MMQFLTYYQH SSGHYHLRVT TVARPLSGPA GDPTLAQSFD QEAAAVLMAR IAVFKAEVDD
550 560 570 580 590 600
GPDVLRWVDR MLIRLCSRFA DYRKDDPTSF RLEKNFTLYP QFMFHLRRSQ FLQVFNNSPD
610 620 630 640 650 660
ETAFYRHVLN HEDVGDSLVM IQPTLDSYSL EHEGSQPVLL DSASIQPAHI LLLDTFFHIL
670 680 690 700 710 720
IFHGETIAEW RKAGYQDQEG YENLKVLLEQ PKEDARELIS DRFPLPRFIV CDAGGSQARF
730 740 750 760
LLSKLNPSTT HTTGGYGGGV TSQIIFTDDV SLQTFMDHLM KLAVSGTS