A2Q898
Gene name |
mcr1 (An01g03570) |
Protein name |
NADH-cytochrome b5 reductase 2 |
Names |
Mitochondrial cytochrome b reductase |
Species |
Aspergillus niger (strain CBS 51388 / FGSC A1513) |
KEGG Pathway |
ang:ANI_1_468014 |
EC number |
1.6.2.2: With a heme protein as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2Q898
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2Q898-F1 | Predicted | AlphaFoldDB |
No variants for A2Q898
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A2Q898 | |||||
No associated diseases with A2Q898
6 regional properties for A2Q898
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | MCM domain | 321 - 540 | IPR001208 |
| domain | AAA+ ATPase domain | 372 - 525 | IPR003593 |
| conserved_site | Mini-chromosome maintenance, conserved site | 439 - 447 | IPR018525 |
| domain | MCM N-terminal domain | 9 - 138 | IPR027925 |
| domain | MCM OB domain | 148 - 277 | IPR033762 |
| domain | MCM, AAA-lid domain | 557 - 639 | IPR041562 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.6.2.2 | With a heme protein as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cytochrome-b5 reductase activity, acting on NAD(P)H | Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFARQAFRCA | QPLKQGFRKY | STEAPKGKSS | LAPIYAAVGI | TGVGVGLYRY | NSATAEAPAA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VDRPKVFKGG | DQGWFDLKLS | EIEVLNHNTK | RLRFEFEDKE | ALSGLQVASA | LLTKFKPADA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KAVIRPYTPT | SDEETPGYID | LVVKVYPNGP | MSEHLHSMNV | GQRLDFKGPI | VKYPWETNKH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NHICLIAGGT | GITPMYQLAR | EIFKNPEDQT | KVTLVFGNVK | EEDILLKKEF | EELENTYPRR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FRAFYVLDNP | PKEWTGGKGY | ISKELLKTVL | PEPKEENIKI | FVCGPPGMYK | AISGTKNSPT |
| 310 | 320 | ||||
| DQGELSGILK | ELGYSKEQVF | KF |