Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2PZF9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2PZF9-F1 | Predicted | AlphaFoldDB |
No variants for A2PZF9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A2PZF9 | |||||
No associated diseases with A2PZF9
4 regional properties for A2PZF9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Homeobox domain | 247 - 311 | IPR001356 |
| domain | Zinc finger, LIM-type | 51 - 112 | IPR001781-1 |
| domain | Zinc finger, LIM-type | 113 - 175 | IPR001781-2 |
| conserved_site | Homeobox, conserved site | 282 - 305 | IPR017970 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| dorsal spinal cord interneuron anterior axon guidance | The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLFHGITGGH | IQGIMEEMER | RSKSADNRLA | KTIQVNGRET | RMPPLSPEKP | TLCAGCGGKI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SDRYYLLAVD | KQWHLRCLKC | CECKLALESE | LTCFAKDGSI | YCKEDYYRRF | SVQRCARCHL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GISASEIVMR | ARESVYHLSC | FTCTTCNKTL | STGDHFGMKE | NLVYRRAHFE | LLVQGDFHSQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LNYTELSAKG | GGLSALPYFT | NGTGAVQKGR | PRKRKSPALG | VDIINYTSGC | NENDTDLDRD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QSYPPSQKTK | RMRTSFKHHQ | LRTTKSYFAI | NHNPDAKDLK | QLAQKTGLTK | RVLQVWFQNA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RAKFRRNLLR | QENGGGDKVE | GPSLSAPAST | DSAALTPTGA | ASTLSDLTSP | SLNVGASVTP |
| 370 | |||||
| NMDSHESGSP | SQTTLTNLF |