A2EK80
Gene name |
TVAG_100140 |
Protein name |
Protein SEY1 homolog 2 |
Names |
|
Species |
Trichomonas vaginalis |
KEGG Pathway |
tva:TVAG_100140 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2EK80
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2EK80-F1 | Predicted | AlphaFoldDB |
No variants for A2EK80
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A2EK80 | |||||
No associated diseases with A2EK80
3 regional properties for A2EK80
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GB1/RHD3-type guanine nucleotide-binding (G) domain | 28 - 245 | IPR030386 |
| domain | Sey1/RHD3-like, three-helix bundle domain | 322 - 594 | IPR046758-1 |
| domain | Sey1/RHD3-like, three-helix bundle domain | 589 - 679 | IPR046758-2 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEQIITGDGA | LVSNLDEKIT | SSGIADAGVD | YHTVAIIGPQ | SSGKSTILNL | LFGTKFATMN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EQRGRQQTTQ | GIHAAKSVND | PILLFDVEGC | DSRERGDSDA | LFERKSALFA | LALSEVLVIN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MWESDIGRYQ | ASNIPMLKTV | FEVNIQLFLA | QNTTKSKILF | VIRDSTAVNF | EAIKFQLNRD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ITNIWDEINL | PDSFKGKQME | DFFEFLYFPI | HHMVIQRDQF | DADVNTLRKW | FNEPPLKDYL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FAEKSTKVVP | GEGLSQYIRN | LWEVINENKE | LNIPSQRTML | ARFKCDENAA | EALSKFNKFV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EENLQRDPDQ | PITIIQDFKP | LCDKSVENAL | KYYHDNSWRY | SEAVVKEREA | QLKQEISDVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LPYFNSQCKL | FCDNTLKRFN | EFISSIDQEL | HVGGTWESDV | QGKIDSLNMD | LKKNIKDTTV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EPFSWNYPDY | EVMKVMFNAT | ESMKGKLVKQ | LEQTIITEQM | RSFDEQANDI | LAKVDNLMWD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NLRNLIRKVS | TETTQNTNQV | LKTNVSGVHA | RNDIKRDFQT | HTISLVRESA | NYIVLKMKNT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FDRTFKYEKN | GRPRVWTRRD | NINQIYENSR | DAGLKVLRHF | TYCRLAESDD | EVKPNDPLTQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| VLIPHERASE | IEDKFERIII | HAYEEARANI | KAQANREQIP | GWAWLATFLC | SSNYIMKLLA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NPIFFALAVI | IGGIYSILRM | LGLQDVAKKT | LLDKFNSLLK | NLTKDENEQE | KEGEENEEPE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EDQPLPNNNR | KRMKLMEKSV | SQEFSQKSIY | KSSEYKGSGD | SLMIPQTSPL | GNNDSPEKPR |
| 790 | |||||
| DSLTRTQSLE | FM |