A2CBJ6
Gene name |
queA |
Protein name |
S-adenosylmethionine:tRNA ribosyltransferase-isomerase |
Names |
Queuosine biosynthesis protein QueA |
Species |
Prochlorococcus marinus (strain MIT 9303) |
KEGG Pathway |
pmf:P9303_21211 |
EC number |
2.4.99.17: Transferring other glycosyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2CBJ6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2CBJ6-F1 | Predicted | AlphaFoldDB |
No variants for A2CBJ6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A2CBJ6 | |||||
No associated diseases with A2CBJ6
No regional properties for A2CBJ6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A2CBJ6 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.99.17 | Transferring other glycosyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity | Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| queuosine biosynthetic process | The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVLDPRDSLL | SSYDYPLDPE | RIAQLPVEPR | HAARLLIVQP | LGMKPPIARH | AEVWDWQEEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RAGDLLVIND | TRVLKARLRV | RRSGGGLAEL | LVLEPRGEGR | WLCLGRPAKR | LRPGDQLWLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ALGEEPIALQ | VISKDSASGG | RVVQFPSHYA | NAEQLELLLE | RYGEVPLPPY | IKCHDPSDSE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RYQTRYASRP | GAVAAPTAGL | HLSDELLEAL | KQRGVMLTSV | TLHVGLGTFR | PVETEDLRHL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QLHSEWVEVR | DEVVAAVMAC | RARAGRVIAV | GTTSVRALEG | AALAGGGFLQ | SFCGPVDLVI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QPGYRFAVVD | GLLTNFHLPK | SSLLLLVSAM | VGRERLLALY | AEAIEHHYRF | FSYGDAMWID |
| 370 | |||||
| PGAVLPAARP | C |