A2C591

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Prochlorococcus marinus (strain NATL1A)
KEGG Pathway
pme:NATL1_20951
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2C591

Entry ID Method Resolution Chain Position Source
AF-A2C591-F1 Predicted AlphaFoldDB

No variants for A2C591

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2C591

No associated diseases with A2C591

7 regional properties for A2C591

Type Name Position InterPro Accession
domain SecA DEAD-like, N-terminal 2 - 397 IPR011115
domain SecA Wing/Scaffold 722 - 935 IPR011116
domain SecA, preprotein cross-linking domain 231 - 353 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 92 - 250 IPR014001
domain SecA motor DEAD 1 - 724 IPR014018
conserved_site SecA conserved site 497 - 512 IPR020937
domain SecA, C-terminal helicase domain 415 - 694 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cellular thylakoid membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane-derived thylakoid membrane The pigmented membrane of a plasma membrane-derived thylakoid.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKKLLGDPN TRKLKRYFPL VSDVNIFEED LLSLSDDDLR TRTSEFRSKL EKVSSPNEEL
70 80 90 100 110 120
SLLDELLPEA FAVVREASKR VLGMRHFDVQ LIGGMVLHEG QIAEMKTGEG KTLVATLPSY
130 140 150 160 170 180
LNALTGRGVH VVTVNDYLAR RDAEWMGQIH RFLGLSVGLV QQSMAPLERK KNYECDITYA
190 200 210 220 230 240
TNSELGFDYL RDNMAADKSE IVQRDFQFCV IDEVDSILID EARTPLIISG QVERSQEKYK
250 260 270 280 290 300
QAAQVVENLK RAIDTSKDGI DPEGDYEVDE KQRSCILTDE GFANTEKLLN VQDLFDPKEP
310 320 330 340 350 360
WAHYVTNALK AKELFIKDVN YIVRNDEAVI VDEFTGRVMP GRRWSDGQHQ AIEAKENLSI
370 380 390 400 410 420
QPETQTLASI TYQNFFLLYP RLSGMTGTAK TEEVEFEKTY KLQTTVVPTN RKISRQDWVD
430 440 450 460 470 480
QVFKTEAAKW RAVAKETADI HQKGRPVLVG TTSVEKSELL STLLSEQQVP HNLLNAKPEN
490 500 510 520 530 540
VEREAEIVAQ AGRAGAVTIA TNMAGRGTDI ILGGNSDYMA RLKIKEILSN RLVKPEEGHK
550 560 570 580 590 600
PPVSPQRKTK SAGFKEEKNK NLSISKQNQS KSFLNIFPVS LTEDTDAKLA SLASKLVKEW
610 620 630 640 650 660
GDRSLSSIEL DDYIATAAEK TPTQDKNIKE LRIAIQLIKN EYEEVLSQEE TNVRRVGGLH
670 680 690 700 710 720
VIGTERHESR RVDNQLRGRA GRQGDLGSTR FFLSLEDNLL RIFGGDRVAG LMNAFRVEED
730 740 750 760 770 780
MPIESGMLTR SLEGAQKKVE TYYYDIRKQI FEYDEVMNNQ RKAVYSERRR VLDGRELKLQ
790 800 810 820 830 840
VIGYGQRTME EIVEAYVNED LPPEEWNLTN LVSKVKEFIY LLEDLKPEDL LGLNKNELKD
850 860 870 880 890 900
FLKEQLRNAY DMKEAKVEQS HPGIMRQAER FFILQQLDTL WREHLQSMDS LKESVGLRGY
910 920 930 940
GQKDPLIEYK NEGYDMFLEM MVNMRRNVIY SMFMFQPAQK KVEA