A2BW33

PR
Gene name
hisA
Protein name
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Names
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Species
Prochlorococcus marinus (strain MIT 9515)
KEGG Pathway
pmc:P9515_07851
EC number
5.3.1.16: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

206-255 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2BW33

Entry ID Method Resolution Chain Position Source
AF-A2BW33-F1 Predicted AlphaFoldDB

No variants for A2BW33

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2BW33

No associated diseases with A2BW33

No regional properties for A2BW33

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A2BW33

Functions

Description
EC Number 5.3.1.16 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.

1 GO annotations of biological process

Name Definition
histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLIPAIDLM NGKCVRLFKG DFNKRKDFSR KPYEQAKYWE EQGAKCIHIV DLDAAKSGYP
70 80 90 100 110 120
SNDQSIKKIA KEVNIPIQIG GGIRSLERIE QLFSYGVDKV IMGTSAIENK ELVKNLSTKF
130 140 150 160 170 180
PRRIIIGIDA KDGKVSTRGW IEQSDVLATD LVKEFSKFEI ASFIVTDINT DGTLEGTNEV
190 200 210 220 230 240
FIKKILEITD IPVIASGGVG AISDLLSLTK FEHLGLCGVI VGKALYENKF KISEANNILS
250
PERLQDIPIN KDYFA