A2BTM1

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Prochlorococcus marinus (strain AS9601)
KEGG Pathway
pmb:A9601_18491
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

515-593 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2BTM1

Entry ID Method Resolution Chain Position Source
AF-A2BTM1-F1 Predicted AlphaFoldDB

No variants for A2BTM1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2BTM1

No associated diseases with A2BTM1

7 regional properties for A2BTM1

Type Name Position InterPro Accession
domain SecA DEAD-like, N-terminal 2 - 397 IPR011115
domain SecA Wing/Scaffold 720 - 933 IPR011116
domain SecA, preprotein cross-linking domain 231 - 353 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 92 - 250 IPR014001
domain SecA motor DEAD 1 - 722 IPR014018
conserved_site SecA conserved site 497 - 512 IPR020937
domain SecA, C-terminal helicase domain 415 - 692 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cellular thylakoid membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane-derived thylakoid membrane The pigmented membrane of a plasma membrane-derived thylakoid.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKLLLGDPN TRKLKRYQPI VEEINFLEEE ISQLTDDELR KETQNLKSNI SAELDFKKQK
70 80 90 100 110 120
ELLEEFLPKA FAIVREASKR VLDMRHFDVQ LIGGMVLNEC QIAEMKTGEG KTLVATLPCY
130 140 150 160 170 180
LNALTGKGVH VVTVNDYLAR RDAEWMGQVH RFLGLSVGLI QQDMNPVERK KNYDCDITYA
190 200 210 220 230 240
TNSELGFDYL RDNMATDISE VVQRKFNYCV IDEVDSILID EARTPLIISG QVERPQEKYQ
250 260 270 280 290 300
KAAELSLALI KAKELSKDGI DPEGDYEVDE KQRSCILTDQ GFAKCEEYLG VNDLYNPQDP
310 320 330 340 350 360
WAHYITNALK AKELFIKDVN YIIKNEEAVI VDEFTGRVMP GRRWSDGQHQ AIEAKESLKI
370 380 390 400 410 420
QPETQTLASI TYQNFFLLYP GLAGMTGTAK TEEVEFEKTY KLESTVIPTN QIRKRQDWSD
430 440 450 460 470 480
QVFKTEIGKW KAVAKETAKI HRDGRPVLVG TTSVEKSELL SSLLSAEKIP HNLLNAKPEN
490 500 510 520 530 540
VEREAEIVAQ AGRAGAVTIA TNMAGRGTDI ILGGNSDYMA RLKLKEILIP LLVKPDNEHK
550 560 570 580 590 600
PPIPKQRNSK SKGGFSRKAG SNLKKKISNS STNLFPCKLD EVIEKKLSLL SDELVKNWGD
610 620 630 640 650 660
KQLSVLELDD RIATAAEKAP TDDKLIRLLR ESLSDVKNEY EKVLIHEEEK VREAGGLHVI
670 680 690 700 710 720
GTERHESRRV DNQLRGRAGR QGDLGSTRFF LSLDDNLLRI FGGDRVANLM NAFRVDEDMP
730 740 750 760 770 780
IESGMLTRSL ESAQKKVETY YYDIRKQVFE YDEVMNNQRK AVYGERLRVL KGIDLKRQVI
790 800 810 820 830 840
GYGERTMIEI VDAYINPDLP PEEWNIEQLI SKVKEFIYLL DDLKVEDINL LSIEELKNYL
850 860 870 880 890 900
QEQLRIAYDL KESQIDKIRP GLMREAERFF ILQQIDNLWR EHLQSMDSLR ESVGLRGYGQ
910 920 930 940
KDPLIEYKNE GYDMFLEMMT NMRRNVIYSM FMFQPKTDKN DKN