A2BJZ8
Gene name |
infB |
Protein name |
Probable translation initiation factor IF-2 |
Names |
|
Species |
Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5) |
KEGG Pathway |
hbu:Hbut_0443 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A2BJZ8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A2BJZ8-F1 | Predicted | AlphaFoldDB |
No variants for A2BJZ8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A2BJZ8 | |||||
No associated diseases with A2BJZ8
7 regional properties for A2BJZ8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 397 - 566 | IPR000795 |
| domain | Small GTP-binding protein domain | 400 - 556 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 1 - 52 | IPR006847-1 |
| domain | Translation initiation factor IF-2, N-terminal | 322 - 372 | IPR006847-2 |
| domain | Initiation factor 2 associated domain, bacterial | 57 - 95 | IPR013575 |
| domain | Translation initiation factor IF- 2, domain 3 | 673 - 787 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 573 - 666 | IPR044145 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEQKTSGRR | LRQPIVVVLG | HVDHGKTTLL | DKIRGTTVAA | KEPGLITQHV | GASFVPASVI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKLAEPLKKI | IPFKLIIPGL | LFIDTPGHEL | FANLRRRGGS | VADFAILVVD | INEGFQPQTY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESIEILRQRR | VPFVVAANKI | DKIPGWRANP | DTPFLISLQK | QAQRVREELE | RRLWDNIISK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LYELGFQADR | FDRIRDFTRT | VAVIPISAKT | GEGIAELLAV | LAGLTQRYLQ | HRLRFAEGPA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KGVILEIREQ | PGLGTAADVV | IYDGVLRKGD | IIVTGGLNGP | VITHVRALLM | PKPLQEIRVA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KRELEPVEEV | YAAAGVRIVA | PGLEEAIAGA | PVFVARDEGE | AKQLAEKVRR | EIEALRIKTE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AEGVIVKADT | LGSLEAMIEA | LRKRDIPIRY | ADVGPVAKRD | VIEAVASREL | NKFYGVILAF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NVKVLPEAEE | EAKKHGITIF | TNNVIYRLLE | DFEKWYKEQV | EAERRKELEK | LVRPGKIRLL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PGYVFRRSNP | AIVGVEVLGG | VIKPGYPLMR | EDGKRIGTIH | QIQDKGKVIH | EARAGMAVAI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SIRGHVMVGR | HIDEGDVLYT | DIPEQHAVLW | LTKFKSELTD | DEMVVLKEII | KIKRKQNPAY |
| 610 | |||||
| AVVLGKPQGA | KP |