A1YQ91

PR
Gene name
ODAM (APIN)
Protein name
Odontogenic ameloblast-associated protein
Names
Apin
Species
Canis lupus familiaris (Dog) (Canis familiaris)
KEGG Pathway
cfa:611755
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1YQ91

Entry ID Method Resolution Chain Position Source
AF-A1YQ91-F1 Predicted AlphaFoldDB

2 variants for A1YQ91

Variant ID(s) Position Change Description Diseaes Association Provenance
rs852448125 85 G>A No EVA
rs852763434 102 G>A No EVA

No associated diseases with A1YQ91

No regional properties for A1YQ91

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A1YQ91

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

8 GO annotations of cellular component

Name Definition
cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
mitotic spindle A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
supramolecular fiber A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

8 GO annotations of biological process

Name Definition
biomineral tissue development Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.
inflammatory response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
odontogenesis of dentin-containing tooth The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
positive regulation of epithelial cell proliferation involved in wound healing Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
positive regulation of gene expression Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
positive regulation of GTPase activity Any process that activates or increases the activity of a GTPase.
positive regulation of protein phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTIILLGLL GATMSAPLIP QRLMSASNSN ELLLNLNNAQ LQPLPFQGPF NSWIPPFSGI
70 80 90 100 110 120
LQQQQQAQIP GLSQFSLSAL DRFAGLFPNQ TPFPGRVSFA QGTQVGQQDP SQPQTPPQTQ
130 140 150 160 170 180
QSPNHVMPYV FSFKMPQEQA QMLQYYPVYM LLPWEQSQQT APQSPPQTGQ QQFEEQMPFY
190 200 210 220 230 240
TQFGYVPVQV EPVMPGGQQQ LALDPVLGTA PETVVMPAGV IPYLRKEVIN FKHANGGIFV
250 260 270
PSTSQTPSTT NYFAPAIDPT ITPELMEKKA KTDYLKEP