Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1YFX5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1YFX5-F1 | Predicted | AlphaFoldDB |
No variants for A1YFX5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1YFX5 | |||||
No associated diseases with A1YFX5
5 regional properties for A1YFX5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SCAN domain | 40 - 152 | IPR003309 |
| domain | Zinc finger C2H2-type | 312 - 339 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 340 - 367 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 368 - 395 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 396 - 418 | IPR013087-4 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome, telomeric region | The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| telomere maintenance via telomere lengthening | Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALDLRTIFQ | CEPSENNLGS | ENSAFQQSQG | PAVQREEGIS | EFSRMVLNSF | QDSNNSYARQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELQRLYRIFH | SWLQPEKHSK | DEIISLLVLE | QFMIGGHCND | KAGVKEKWKS | SGKNLERFIE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DLTDDSINPP | ALVHVHMQGQ | EALFSEDMPL | RDVIVHLTKQ | VNAQTTREAN | MGTPSQTSQD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TSLETGQGYE | DEQDGWNSSL | KTTQVNENIT | NQGDQIVSLI | IIQEENSPRP | EEGGVSSDNP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YNSKRAELVT | ARSQEGSING | ITFQGVPMVM | GAGCISQPEQ | SSPESALTHQ | SNEGNSTCEV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HQKGSHGVRK | SYKCEECPKV | FKYLCHLLAH | QRRHRNERPF | VCPECQKGFF | QISDLRVHQI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IHTGKKPFTC | SICKKSFSHK | TNLRSHERIH | TGEKPYTCPF | CKTSYRQSST | YHRHMRTHEK |
| 430 | |||||
| ITVPSVPSTP | EAS |