A1YFW6
Gene name |
ZNF449 |
Protein name |
Zinc finger protein 449 |
Names |
|
Species |
Pan paniscus (Pygmy chimpanzee) (Bonobo) |
KEGG Pathway |
pps:100986245 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1YFW6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1YFW6-F1 | Predicted | AlphaFoldDB |
No variants for A1YFW6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1YFW6 | |||||
No associated diseases with A1YFW6
8 regional properties for A1YFW6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SCAN domain | 26 - 134 | IPR003309 |
| domain | Zinc finger C2H2-type | 323 - 350 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 351 - 378 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 379 - 406 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 407 - 434 | IPR013087-4 |
| domain | Zinc finger C2H2-type | 435 - 462 | IPR013087-5 |
| domain | Zinc finger C2H2-type | 463 - 490 | IPR013087-6 |
| domain | Zinc finger C2H2-type | 491 - 513 | IPR013087-7 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| sequence-specific double-stranded DNA binding | Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| spermatogonial cell division | The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVALGCAIQ | ASLNQGSVFQ | EYDTDCEVFR | QRFRQFQYRE | AAGPHEAFNK | LWELCCQWLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PKMRSKEQIL | ELLVLEQFLT | ILPTEIETWV | REHCPENRER | VVSLIEDLQR | ELDIPEQQVD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MHDMLLEELA | PVGTAHIPPT | MHLESPALQV | MGPAQEAPVA | EAWIPQAGPP | ELNYSATGEC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QNFLDPGYPL | PKLDMNFSLE | NREEPWVKEL | QDSKEMKQLL | DSKIGFEIGI | ENEEDTSKQK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KMETMYPFIV | TLEGNALQGP | ILQKDYVQLE | NQWETPPEDL | QRDLAKLVDQ | QNPTLGETPE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NSNLEEPLNP | KPHKKKSPGE | KPHRCPQCGK | CFARKSQLTG | HQRIHSGEEP | HKCPECGKRF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRSSDLYRHQ | RLHTGERPYE | CTVCKKRFTR | RSHLIGHQRT | HSEEETYKCL | ECGKSFCHGS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLKRHLKTHT | GEKPHRCHNC | GKSFSRLTAL | TLHQRTHTEE | RPFKCNYCGK | SFRQRPSLVI |
| 490 | 500 | 510 | |||
| HLRIHTGEKP | YKCTHCSKSF | RQRAGLIMHQ | VTHFRGLI |