A1YEQ3
Gene name |
ZNF449 |
Protein name |
Zinc finger protein 449 |
Names |
|
Species |
Gorilla gorilla gorilla (Western lowland gorilla) |
KEGG Pathway |
ggo:101141177 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1YEQ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1YEQ3-F1 | Predicted | AlphaFoldDB |
No variants for A1YEQ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1YEQ3 | |||||
No associated diseases with A1YEQ3
8 regional properties for A1YEQ3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SCAN domain | 26 - 134 | IPR003309 |
| domain | Zinc finger C2H2-type | 323 - 350 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 351 - 378 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 379 - 406 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 407 - 434 | IPR013087-4 |
| domain | Zinc finger C2H2-type | 435 - 462 | IPR013087-5 |
| domain | Zinc finger C2H2-type | 463 - 490 | IPR013087-6 |
| domain | Zinc finger C2H2-type | 491 - 513 | IPR013087-7 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| metal ion binding | Binding to a metal ion. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVALGCAIQ | ASLNQGSVFQ | EYDTDCEVFR | QRFRQFQYRE | AAGPHEAFNK | LWELCCQWLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PKMRSKEQIL | ELLVLEQFLT | ILPTEIETWV | REHCPENRER | VVSLIEDLQR | ELEIPEQQVD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MHDMLLEELA | PVGTAHIPPT | MHLESPALQV | MGPAQEAPVT | EAWIPQAGPP | ELNYGATGEC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QNFLDPGYPL | PKLDMNFSLE | NREEPWVKEL | QDSKEMKQLL | DSKIGFEIGI | ENEEDTSKQK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KMETMYPFIV | TLEGNALQGP | ILQKDYVQLE | NQWETPPEDL | QTDLAKLVDQ | QNPTLGETPE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NSNLEEPLNP | KPHKKKSPGE | KPHRCPQCGK | CFARKSQLTG | HQRIHSGEEP | HKCPECGKRF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRSSDLYRHQ | RLHTGERPYE | CTVCKKRFTR | RSHLIGHQRT | HSEEETYKCL | ECGKSFCHGS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLKRHLKTHT | GEKPHRCHNC | GKSFSRLTAL | TLHQRTHTEE | RPFKCNYCGK | SFRQRPSLVI |
| 490 | 500 | 510 | |||
| HLRIHTGEKP | YKCTHCSKSF | RQRAGLIMHQ | VTHFRGLI |