A1XFW4

PR
Gene name
accD
Protein name
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
Names
ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta
Species
Nuphar advena (Common spatterdock) (Nuphar lutea subsp advena)
KEGG Pathway
EC number
2.1.3.15: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

159-238 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1XFW4

Entry ID Method Resolution Chain Position Source
AF-A1XFW4-F1 Predicted AlphaFoldDB

No variants for A1XFW4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1XFW4

No associated diseases with A1XFW4

2 regional properties for A1XFW4

Type Name Position InterPro Accession
domain Acetyl-coenzyme A carboxyltransferase, N-terminal 221 - 483 IPR011762
domain Acetyl-CoA carboxylase 273 - 438 IPR034733

Functions

Description
EC Number 2.1.3.15 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Plastid, chloroplast stroma
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
acetyl-CoA carboxylase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
chloroplast stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

4 GO annotations of molecular function

Name Definition
acetyl-CoA carboxylase activity Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carboxyl- or carbamoyltransferase activity Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
malonyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKWWLNSML SNEDLGRRCG LSASLGPIGN TSGSEEPITN DNEKNIHSWS GRGSYSYSNV
70 80 90 100 110 120
DYLLGLDGVK DIWSLISGDT FWVRDSNGDS YSVYFDIENK IFEIDTDSYF LGELESLFSS
130 140 150 160 170 180
YLNLNSGSKD YNRYYDQYVY DTRHSWKNHI NSCIDSYIRS ETNMDSCISN GSNNSSDNYI
190 200 210 220 230 240
YSYICSDSER GSDRGSSNLK TSVSDFGRHS DLDRNLKYGH LWVQCENCYG LNYKKFFSSK
250 260 270 280 290 300
MNICEQCGYH LKMSSSDRIE LLIDPGTWDP MDENMVSIDP IEFHSEEEPY RDRINSYQIE
310 320 330 340 350 360
TGLAEAVQTG IGKLNGIPIA IGVMDFKFMG GSMGSVVGEK ITRLIEYATD RSLPVIMVCA
370 380 390 400 410 420
SGGARMQEGS LSLMQMAKIS SALYNYQSNK KLFYVSILTS PTTGGVTASF GMLGDIIIAE
430 440 450 460 470 480
PNAYIAFAGK RVIEQTLKKT VPEGSQVAEY SFHKGLFDPI VPRNLLKGVP SELFQFHGFF
PRP