A1WLP8

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Verminephrobacter eiseniae (strain EF01-2)
KEGG Pathway
vei:Veis_2817
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

685-757 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1WLP8

Entry ID Method Resolution Chain Position Source
AF-A1WLP8-F1 Predicted AlphaFoldDB

No variants for A1WLP8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1WLP8

No associated diseases with A1WLP8

2 regional properties for A1WLP8

Type Name Position InterPro Accession
domain Nicotinate phosphoribosyltransferase, N-terminal domain 13 - 130 IPR040727
domain Nicotinate/nicotinamide phosphoribosyltransferase 169 - 395 IPR041525

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGIFNKVTKT FQWGDQTVVM ETGEIARQAS GAVLVSIDDT VVLATVVASR SIKPGQDFFP
70 80 90 100 110 120
LTVDYIEKTY AAGKIPGSFF KREAKPSEHE TLTSRLIDRP LRPLFPQGFF NEVHLVIHTL
130 140 150 160 170 180
SLNPEVDADI AALIASSAAL ALSGIPFNGP IGAARVGYIQ GEYRLNPGPT ARKSSQLDLV
190 200 210 220 230 240
VAGTEAAVLM VESEAQQLSE EIMLGAVVFG HQQGKVAIDA IHELVHAAGK PVWQWEAPAR
250 260 270 280 290 300
DEALIARVAA LADDKLRAAY QIRNKQARTE ACRAAYAAVL AQLQADGVEC DTVKAEGLLF
310 320 330 340 350 360
DIEAGIVRSQ ILAGEPRIDG RDTRTVRPIE IRAGVLPRAH GSALFTRGET QALAVATLGT
370 380 390 400 410 420
ERDAQRIDAL AGEYDDRFML HYNMPPFATG EVGRMGSTKR REIGHGRLAK RALVAVLPTK
430 440 450 460 470 480
EEFPYTMRVV SEITESNGSS SMASVCGGCL SLMDAGVPMK AHVAGIAMGL IKDGNRFAVL
490 500 510 520 530 540
TDILGDEDHL GDMDFKVAGT TAGITALQMD IKIQGITREI MQVALAQAKE ARMHILGKMQ
550 560 570 580 590 600
QAIGQAKTEV SNFAPKLYTM KINAEKIRDV IGKGGAVIRA LTEETGCQIN IEEDGTITIA
610 620 630 640 650 660
ATDAAKADIA KRRIEQITAE IEIGKIYEGP VTKLLDFGAL INLLPGKDGL LHISQIAHER
670 680 690 700 710 720
VERVSDYLSE GQIVRVKVME ADERGRVKLS MKVLAERPAP GSDRFGTGSE RPAPGSDRPA
730 740 750
LAEREPRREM RDHGHPPSEQ QQQQSPPADT GSGQRVG