A1V4V8

PR
Gene name
pgi
Protein name
Glucose-6-phosphate isomerase
Names
GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI
Species
Burkholderia mallei (strain SAVP1)
KEGG Pathway
bmv:BMASAVP1_A1942
EC number
5.3.1.9: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

409-478 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1V4V8

Entry ID Method Resolution Chain Position Source
AF-A1V4V8-F1 Predicted AlphaFoldDB

No variants for A1V4V8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1V4V8

No associated diseases with A1V4V8

5 regional properties for A1V4V8

Type Name Position InterPro Accession
domain Alpha-D-phosphohexomutase, C-terminal 472 - 532 IPR005843
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain I 42 - 169 IPR005844
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain II 204 - 305 IPR005845
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain III 316 - 436 IPR005846
conserved_site Alpha-D-phosphohexomutase, conserved site 137 - 146 IPR016066

Functions

Description
EC Number 5.3.1.9 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
carbohydrate derivative binding Binding to a carbohydrate derivative.
glucose-6-phosphate isomerase activity Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.

2 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLNSLPVWP ALQAHYEEIR DAHLRDWFAP ANDRAPTRAE RFTFEGGGLA ADFSKNRLTD
70 80 90 100 110 120
ATLALLVRLA REAGVEARRD AMFAGETVNP TEGRAALHTA LRANAPDAPF QAQVAAERAK
130 140 150 160 170 180
MARFADAVRS GAWTGYTGKR IRHVVNIGIG GSDLGPKMVV HALHHVATPD IATHFVSNVD
190 200 210 220 230 240
GADLARVLER IDPEETLAII VSKTFTTLET MTNARSLRDW FVANGCPEGA LAKHFVGVSA
250 260 270 280 290 300
NPAEVVKFGI AEANVFEMWD WVGGRYSLWS AVGLSIMIAI GPERFDELLA GARDMDEHFR
310 320 330 340 350 360
TAPLERNLPV LQGLVGIWYR NFFGAQSYLV APYSEALHYL PSYLQQLEME SNGKSARIDG
370 380 390 400 410 420
AFVDYPTSAV TWGEPGTNGQ HAFFQMLHQG PTLVPIDFIA VLTPEHPLAS HHPKLLANCF
430 440 450 460 470 480
AQSEALMLGR TLDEARKIAG PAKPELAPHL TFPGNRPTTT LLVDALTPRT LGALIALYEH
490 500 510 520 530
KVLVQAAVWN INPFDQWGVE LGKILGKVVE ADLTAAQVDP AKHDSSTSAL IARARKALGE