A1UA55
Gene name |
nhaA1 |
Protein name |
Na(+)/H(+) antiporter NhaA 1 |
Names |
Sodium/proton antiporter NhaA 1 |
Species |
Mycobacterium sp (strain KMS) |
KEGG Pathway |
mkm:Mkms_0497 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1UA55
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1UA55-F1 | Predicted | AlphaFoldDB |
No variants for A1UA55
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1UA55 | |||||
No associated diseases with A1UA55
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| antiporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
| sodium ion transmembrane transporter activity | Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of pH | Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTEASARTIG | PLPSRFSRDP | KTPRSTDNAA | AALLLAFTVL | AILWANSPWA | QSYSIFWDTD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VAVSFGEYRA | ELSVKHLVND | GLMAFFFFIV | GLEVKSEFVI | GELTDRSRAA | VPVVAAIAGL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IVPAVIFLTF | NPSGPDAQAW | GVVISTDTAF | LVGALAVIKP | KFPARLRIFL | LTLAVVDDVG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALGAIALFYT | DDLKLAPLAV | AALLIAALAM | VRRLPSLRGP | AYAVLGFALW | IALYLAHVHP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TLAGVAVAVL | IPVFTPERRQ | VEQTVDLVRA | FRQSPNPQYA | RAVTRGLRES | ISINERLQTA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VGPYVSFVVL | PIFALANAGV | HLDEQTITAA | MSSTLTWGIV | AGLVVGKFVG | ITAATALMSA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TGWGQLAPGL | SLRRVAGGAA | LSGIGFTISL | FIVDVAIEDP | ARQDEARVGV | LIASVLAFTL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SWALFRITDW | ISPPEPVGLT | LVRPVDPERD | HIRGDPDAPL | VLVEYGDYEC | PFCGRATGAI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DEVRTHFGDD | LLYVWRHFPL | ERAHPRSFDA | ARASEGAAAQ | GKFFEMGREL | FAHQDDLEWS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DMYRYAVAIG | LDIEQFDQDV | RVHASKVLHR | VRDDAQDAEV | MDLNSTPTFF | VNGKRHKGPW |
| 610 | |||||
| DAASLIRALE | AGR |