A1U3E9

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter aquaeolei)
KEGG Pathway
maq:Maqu_2443
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

585-658 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A1U3E9

Entry ID Method Resolution Chain Position Source
AF-A1U3E9-F1 Predicted AlphaFoldDB

No variants for A1U3E9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A1U3E9

No associated diseases with A1U3E9

9 regional properties for A1U3E9

Type Name Position InterPro Accession
domain Helicase, C-terminal 435 - 633 IPR001650
conserved_site SEC-C motif 892 - 910 IPR004027
domain SecA DEAD-like, N-terminal 6 - 400 IPR011115
domain SecA Wing/Scaffold 615 - 827 IPR011116
domain SecA, preprotein cross-linking domain 228 - 356 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 617 IPR014018
conserved_site SecA conserved site 498 - 513 IPR020937
domain SecA, C-terminal helicase domain 418 - 587 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFTKLATKMF GSKNAREIKR MRKVVTRINE LEEQFGALSD TELQGKTAEF RRRLDEGEAL
70 80 90 100 110 120
DSLLPEVFAT VREASRRVMG MRHYDVQLIG GMTLHEGRIA EMKTGEGKTL VATAAVYLNA
130 140 150 160 170 180
LPGKGVHVVT VNDYLARRDA EWMGKLYRFL GMQVGVVASG QPPEEKRAAY QADITYGTNN
190 200 210 220 230 240
EFGFDYLRDN MAFSIEDKVQ RGLNFAIVDE VDSILIDEAR TPLIISGAAE DSSKLYQAVN
250 260 270 280 290 300
ALVPSLEKGE VSEEGESSGD FTIDEKSRQV ELTESGHEKV EDLLLGQGLL KEGESLYSAA
310 320 330 340 350 360
NLSLLHHVHS ALRAHHLFQK DVDYIVQGGQ VVIVDEHTGR TMPGRRWSEG LHQAIEAKEG
370 380 390 400 410 420
LKIQAESQTL ASTTFQNYFR LYDKLAGMTG TADTEAFEFR QIYGLDVVVI PPNKPIQRID
430 440 450 460 470 480
YNDLVYLTQE EKFHAIIDEI KDVTAEGRPI LVGTASIEAS ELLSMLLKKA RIDHKILNAK
490 500 510 520 530 540
QHESEALIIA QAGRPGAVTI ATNMAGRGTD IVLGGNWEYE VAALDNPSEE EVARMKAEWT
550 560 570 580 590 600
ERHNQVLDAG GLHIIGTERH ESRRIDNQLR GRAGRQGDPG SSRFFLSLED NLMRIFAPER
610 620 630 640 650 660
VKNLMQAMGM KKGEAIEHRM VTNAIEKSQR KVEGRNFDMR KTLLEYDDVA NDQRTVIYEQ
670 680 690 700 710 720
RNEVMASNDI SEMIDTIRED VVDSVVSEFI PPQSMPEQWD VQGLEAQLQS EMAIELPIQQ
730 740 750 760 770 780
WLKDDNKLYE DNLRQKILDA IVAEYKAKEE VAGSEAMRKF EKQVFLQVLD TLWKEHLSNM
790 800 810 820 830 840
DHLRRGIHLR GYAQKNPKQE YKREAFNLFE TMLDTMKRDV TRVLCHVRVQ SQEEMAEIER
850 860 870 880 890 900
RRKEELEREM ARAKLRHEQA SAAQAEGEGD DGQQGQQATP ETFVRQERKV GRNEPCPCGS
910
GKKYKQCCGK VS